A fluorescent DNA probe for necrotic and apoptotic cells
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Nuclear Green™ DCS1

Item No. 25171

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Emission
526 nm
Excitation
503 nm
Formulation (Request formulation change)
A solution in DMSO
Solubility(Learn about Variance in Solubility)
DMSO: Soluble
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µl

    $156

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    Product Description

    Nuclear Green™ DCS1 is a DNA-selective, cell-impermeant dye that is used to label DNA content in live or fixed necrotic and apoptotic cells. Upon binding to double-stranded DNA, Nuclear Green™ DCS1 fluoresces, and this fluorescence can be measured using fluorescence microscopy, microplate fluorometry, or flow cytometry. It has been used to label necrotic and apoptotic bovine monocyte-derived macrophages (bMDM) following infection with M. bovis AF2122.1 Nuclear Green™ DCS1 displays excitation/emission maxima of 503/526 nm, respectively.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Jensen, K., Gallagher, I.J., Johnston, N., et al. Variation in the early host-pathogen interaction of bovine macrophages with divergent Mycobacterium bovis strains in the United Kingdom. Infect. Immun. 86(3), e00385-e00417 (2018).