A methylated form of 2-HOBA
Related Products
Isomer(s)
253515-methyl-2-HOBA (hydrochloride)
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N-methyl-2-HOBA (hydrochloride)

Item No. 25399

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[(methylamino)methyl]-phenol, monohydrochloride
CAS Number
63989-87-7
Synonyms
  • N-methyl-2-(Aminomethyl)phenol
  • N-methyl-2-Hydroxybenzylamine
  • 2-hydroxy-N-Methylbenzylamine
Molecular Formula
C8H11NO • HCl
Formula Weight
173.6
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 50 mg/mlDMSO: 50 mg/mlEthanol: 20 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
217, 278 nm
SMILES
CNCC1=CC=CC=C1O.Cl
InChi Code
InChI=1S/C8H11NO.ClH/c1-9-6-7-4-2-3-5-8(7)10;/h2-5,9-10H,6H2,1H3;1H
InChi Key
UDXXNWDSBJINMV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 g

    $203

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    Product Description

    N-methyl-2-HOBA is a methylated form of the isoketal scavenger 2-HOBA (Item No. 25357).1 It has low reactivity with isoketals and has no effect on hypertension induced by angiotensin II (Item No. 17150). N-methyl-2-HOBA has been used as a negative control for the activity of 2-HOBA in a mouse model of hypertension.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kirabo, A., Fontana, V., de Faria, A.P.C., et al. DC isoketal-modified proteins activate T cells and promote hypertension. J. Clin. Invest. 124(10), 4642-4656 (2014).