A terpenylated diketopiperazine with anticancer activity
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Drimentine B

Item No. 25451

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(5aS,6aS,11aS)-6a-[[(1S,4aS,8aS)-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]methyl]-6,6a,11,11a-tetrahydro-3H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-5,13(2H,5aH)-dione
CAS Number
204398-91-4
Molecular Formula
C31H39N3O2
Formula Weight
485.7
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: solubleDMSO: solubleEthanol: solubleMethanol: soluble
SMILES
O=C([C@@](C[C@]1(C[C@@]2([H])C(CC[C@]3([H])[C@]2(C)CCCC3(C)C)=C)[C@@]4([H])NC5=C1C=CC=C5)([H])N4C6=O)N7C6=CCC7
InChi Code
InChI=1S/C31H39N3O2/c1-19-12-13-25-29(2,3)14-8-15-30(25,4)21(19)17-31-18-24-26(35)33-16-7-11-23(33)27(36)34(24)28(31)32-22-10-6-5-9-20(22)31/h5-6,9-11,21,24-25,28,32H,1,7-8,12-18H2,2-4H3/t21-,24-,25-,28-,30+,31-/m0/s1
InChi Key
SUUCBHITXBJOGT-JMGSXGSMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Drimentine B is a terpenylated diketopiperazine originally isolated from Actinomycete bacteria that has anticancer activity.1 It inhibits the proliferation of NS-1 murine β lymphocyte myeloma cells by 41 and 59% in vitro when used at concentrations of 50 and 100 µg/ml, respectively.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lacey, E., Power, M., Wu, Z., et al. Terpenylated diketopiperazines, (drimentines). WO1998009968A1, (1998).