An Analytical Reference Standard
Related Products
Contained In
37649Kratom Alkaloids Mixture
Isomer(s)
40237Isopteropodine
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Mitraphylline

Item No. 25528

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(1'S,3R,4'aS,5'aS,10'aR)-1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, methyl ester
CAS Number
509-80-8
Molecular Formula
C21H24N2O4
Formula Weight
368.4
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 5 mg/mlDMSO:PBS (pH 7.2) (1:2): 0.33 mg/mlEthanol: slightly soluble
λmax
243 nm
SMILES
O=C1NC2=C(C=CC=C2)[C@]31CCN4C[C@]5([H])[C@H](C)OC=C(C(OC)=O)[C@@]5([H])C[C@]43[H]
InChi Code
InChI=1S/C21H24N2O4/c1-12-14-10-23-8-7-21(16-5-3-4-6-17(16)22-20(21)25)18(23)9-13(14)15(11-27-12)19(24)26-2/h3-6,11-14,18H,7-10H2,1-2H3,(H,22,25)/t12-,13-,14+,18-,21+/m0/s1
InChi Key
JMIAZDVHNCCPDM-DAFCLMLCSA-N
Origin
Plant/Uncaria tomentosa
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Mitraphylline (Item No. 25528) is an analytical reference standard that is structurally similar to known opioids. Mitraphylline has been found in M. speciosa (Kratom in Thai).1 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sudmoon, R., Tanee, T., Wonok, W., et al. Discovery of rhynchophylline and mitraphylline in two Thai Mitragyna species and the investigation of their biological activity via opioid gene expression analysis. Sci. Rep. 15(1), 5865 (2025).

    Product Citations

    Lei, S., Lu, J., Cheng, A., et al. Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) and Uncaria tomentosa (cat’s claw). Drug Metab. Dispos. 51(5), 629-636 (2023).