A phospholipid
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1-Stearoyl-2-Docosahexaenoyl-sn-glycero-3-PC

Item No. 25595

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(7R,12Z,15Z,18Z,21Z,24Z,27Z)-4-hydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxooctadecyl)oxy]methyl]-3,5,8-trioxa-4-phosphatriaconta-12,15,18,21,24,27-hexaen-1-aminium, 4-oxide, inner salt
CAS Number
59403-52-0
Synonyms
  • DHA-PC
  • 18:0/22:6 PC
  • PC(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
  • 1-Stearoyl-2-Docosahexaenoyl-sn-glycero-3-Phosphatidylcholine
  • 1-Stearoyl-2-Docosahexaenoyl-sn-glycero-3-Phosphocholine
Molecular Formula
C48H84NO8P
Formula Weight
834.2
Purity
≥95%
Formulation (Request formulation change)
A 10 mg/ml solution in chloroform
Solubility(Learn about Variance in Solubility)
Chloroform: soluble
SMILES
[O-]P(OC[C@H](OC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)COC(CCCCCCCCCCCCCCCCC)=O)(OCC[N+](C)(C)C)=O
InChi Code
InChI=1S/C48H84NO8P/c1-6-8-10-12-14-16-18-20-22-23-24-25-27-29-31-33-35-37-39-41-48(51)57-46(45-56-58(52,53)55-43-42-49(3,4)5)44-54-47(50)40-38-36-34-32-30-28-26-21-19-17-15-13-11-9-7-2/h8,10,14,16,20,22,24-25,29,31,35,37,46H,6-7,9,11-13,15,17-19,21,23,26-28,30,32-34,36,38-45H2,1-5H3/b10-8-,16-14-,22-20-,25-24-,31-29-,37-35-/t46-/m1/s1
InChi Key
FAUYAENFVCNTAL-PFFNLMTBSA-N
Side Chain Carbon Sum
40:6
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    5 mg

    $81

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    10 mg

    $152

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    25 mg

    $337

    Add
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    Product Description

    1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC is a phospholipid containing stearic acid (Item No. 10011298) and docosahexaenoic acid (DHA; Item No. 90310) at the sn-1 and sn-2 positions, respectively. It has been used in the study of lipid membrane organization and dynamics.1 The levels of 1-stearoyl-2-docosahexaenoyl-sn-glycero-3-PC are decreased in the L5 anterior horn in a superoxide dismutase 1 mutant (SOD1G93A) transgenic mouse model of amyotrophic lateral sclerosis (ALS) at the terminal stage of disease.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Leng, X., Kinnun, J.J., Cavazos, A.T., et al. All n-3 PUFA are not the same: MD simulations reveal differences in membrane organization for EPA, DHA and DPA. Biochim. Biophys. Acta Biomembr. 1860(5), 1125-1134 (2018).

    2. Arima, H., Omura, T., Hayasaka, T., et al. Reductions of docosahexaenoic acid-containing phosphatidylcholine levels in the anterior horn of an ALS mouse mode. Neuroscience 297, 127-136 (2015).