An alkyl glyceryl ether
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1-O-Hexadecyl-sn-glycerol

Item No. 25723

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-(hexadecyloxy)-1,2S-propanediol
CAS Number
506-03-6
Synonyms
  • α-Chimyl Alcohol
  • (S)-(+)-Chimyl Alcohol
Molecular Formula
C19H40O3
Formula Weight
316.5
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 16 mg/mlDMSO: 0.16 mg/mlEthanol: 5 mg/ml
SMILES
CCCCCCCCCCCCCCCCOC[C@@H](O)CO
InChi Code
InChI=1S/C19H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-22-18-19(21)17-20/h19-21H,2-18H2,1H3/t19-/m0/s1
InChi Key
OOWQBDFWEXAXPB-IBGZPJMESA-N
Side Chain Carbon Sum
16:0
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    100 mg

    $90

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    250 mg

    $145

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    500 mg

    $262

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    1 g

    $392

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    Product Description

    1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether.1,2 It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 (PGE2; Item No. 14010) in normal human epidermal keratinocytes (NHEKs).1 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yokota, M., Yahagi, S., Tokudome, Y., et al. Chimyl alcohol suppresses PGE2 synthesis by human epidermal keratinocytes through the activation of PPAR-γ. J. Oleo. Sci. 67(4), 455-462 (2018).

    2. Maulik, N., Tosaki, A., Engelman, R.M., et al. Myocardial salvage by chimyl alcohol: Possible role of peroxisomal dysfunction in reperfusion injury. Ann. N. Y. Acad. Sci. 723(1), 380-384 (1994).