A sesquiterpene
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α-Copaene

Item No. 25770

Technical Information
Formal Name
(1R,2S,6S,7S,8S)-1,3-dimethyl-8-(1-methylethyl)-tricyclo[4.4.0.02,7]dec-3-ene
CAS Number
3856-25-5
Synonyms
  • (–)-Copaene
Molecular Formula
C15H24
Formula Weight
Purity
≥95%
Chloroform: Slightly SolubleMethanol: Slightly Soluble
SMILES
CC1=CC[C@]2([H])[C@]3(C)[C@@]1([H])[C@@]2([H])[C@H](C(C)C)CC3
InChi Code
InChI=1S/C15H24/c1-9(2)11-7-8-15(4)12-6-5-10(3)14(15)13(11)12/h5,9,11-14H,6-8H2,1-4H3/t11-,12-,13-,14+,15+/m0/s1
InChi Key
VLXDPFLIRFYIME-BTFPBAQTSA-N
Origin
Plant/Angelica oil
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    Product Description

    α-Copaene is a sesquiterpene found in a variety of plants, including Cannabis, that has antiproliferative and antioxidant properties.1,2 It inhibits proliferation of primary rat neurons and N2a rat neuroblastoma cells in a concentration-dependent manner and cultured human lymphocytes when used at concentrations greater than 100 mg/L.2,3 α-Copaene (25 mg/L) increases total antioxidant capacity in primary rat neurons and N2a neuroblastoma cells, as well as cultured human lymphocytes, when used at concentrations of 50 and 100 mg/L.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Marchini, M., Charvoz, C., Dujourdy, L., et alMultidimensional analysis of cannabis volatile constituents: Identification of 5,5-dimethyl-1-vinylbicyclo[2.1.1]hexane as a volatile marker of hashish, the resin of Cannabis sativa L. J. Chromatogr. A. 1370, 200-215 (2014).

    2. Türkez, H., Çelik, K., and Toǧar, B. Effects of copaene, a tricyclic sesquiterpene, on human lymphocytes cells in vitro. Cytotechnology 66(4), 597-603 (2014).

    3. Turkez, H., Togar, B., Tatar, A., et alCytotoxic and cytogenetic effects of α-copaene on rat neuron and N2a neuroblastoma cell lines. Biologia 69(7), 936-942 (2014).