A bicyclic monoterpene
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Isomer(s)
23165(+)-3-Carene 25768(±)-3-Carene
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Sabinene

Item No. 25777

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-methylene-1-(1-methylethyl)-bicyclo[3.1.0]hexane
CAS Number
3387-41-5
Synonyms
  • NSC 407278
Molecular Formula
C10H16
Formula Weight
136.2
Purity
≥98%
Formulation (Request formulation change)
A neat oil
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlEthanol: 20 mg/mlEthanol:PBS (pH 7.2)(1:2): 0.33 mg/ml
SMILES
C=C1C2C(C2)(C(C)C)CC1
InChi Code
InChI=1S/C10H16/c1-7(2)10-5-4-8(3)9(10)6-10/h7,9H,3-6H2,1-2H3
InChi Key
NDVASEGYNIMXJL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    25 mg

    $65

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    50 mg

    $119

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    100 mg

    $174

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    250 mg

    $401

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    Product Description

    Sabinene is a bicyclic monoterpene found in a variety of plants, including Cannabis, that has antifungal and anti-inflammatory properties.1,2,3 It inhibits the growth of various fungi in vitro, including several species of Candida, Trichophyton, and Aspergillus (MICs = 0.16-5 μl/ml).3 Sabinene (0.32 μl/ml) prevents increases in nitrite production in RAW 264.7 macrophages stimulated by LPS and IFN-γ. It is cytotoxic to RAW 264.7 macrophages and HaCat keratinocytes when used at a concentration of 1.25 μl/ml. Formulations containing sabinene have been used as perfume additives.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Marchini, M., Charvoz, C., Dujourdy, L., et al. Multidimensional analysis of cannabis volatile constituents: Identification of 5,5-dimethyl-1-vinylbicyclo[2.1.1]hexane as a volatile marker of hashish, the resin of Cannabis sativa L. J. Chromatogr. A. 1370, 200-215 (2014).

    2. Cao, Y., Zhang, H., Liu, H., et al. Biosynthesis and production of sabinene: Current state and perspectives. Appl. Microbiol. Biotechnol. 102(4), 1535-1544 (2018).

    3. Valente, J., Zuzarte, M., Gonçalves, M.J., et al. Antifungal, antioxidant and anti-inflammatory activities of Oenanthe crocata L. essential oil. Food Chem. Toxicol. 62, 349-354 (2013).