For immunochemical detection of H2AX Phospho-Ser139
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H2AX Phospho-Ser139 (1H2) Monoclonal Antibody

Item No. 25781

Product Insert (PDF)
Technical Information
Immunogen
Recombinant TLF protein
Clone Designation
14HH2-1H2
Liquid ascite
Host
Mouse
Isotype
IgG1κ
Applications
ELISA, ICC, and WB
Species Reactivity
(+) Mouse Histone H2 phosphorilated on Ser139(+) Human Histone H2 phosphorilated on Ser139
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    Product Description

    DNA double-strand break (DSB) are leading to the early phosphorylation of histone H2AX. Phosphorylated γ-H2AX is the first step in the recruitment of the DNA repair protein at the foci site. They are consequently very good biomarkers of DSB as well as check point for cell cycle arrest following DSB. Measuring γ-H2AX phosphorylation has become a gold standard in DNA damage and repair for DSB events.

    WARNING This product is not for human or veterinary use.