An alkaloid
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Isomer(s)
25287Cryogenine
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Lythrine

Item No. 25804

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(4aS,6S,9Z,20S)-2,3,4,4a,5,6-hexahydro-14-hydroxy-17,18-20H-6,20-methano-11,15-metheno-1H,8H-benzo[g]pyrido[2,1-d][1,5]oxaazacyclohexadecin-8-one
CAS Number
5286-10-2
Synonyms
  • (+)-Lythrine
Molecular Formula
C26H29NO5
Formula Weight
435.5
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlEthanol: 1 mg/ml
λmax
284 nm
SMILES
COC1=CC([C@@]2([H])N3CCCC[C@@]3([H])C[C@@]4([H])C2)=C(C5=CC(/C=C\C(O4)=O)=CC=C5O)C=C1OC
InChi Code
InChI=1S/C26H29NO5/c1-30-24-14-19-20(15-25(24)31-2)22-13-18(12-17-5-3-4-10-27(17)22)32-26(29)9-7-16-6-8-23(28)21(19)11-16/h6-9,11,14-15,17-18,22,28H,3-5,10,12-13H2,1-2H3/b9-7-/t17-,18-,22-/m0/s1
InChi Key
WCZWUYYJZVBKDZ-ZQMQQCDVSA-N
Origin
Plant/Heimia salicifolia
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    1 mg

    $69

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    5 mg

    $297

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    10 mg

    $525

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    25 mg

    $1,146

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    Product Description

    Lythrine is an alkaloid originally isolated from H. salicifolia that inhibits prostaglandin synthetase (IC50 = 469 μM).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lema, W.J., Blankenship, J.W., and Malone, M.H. Prostaglandin synthetase inhibition by alkaloids of Heimia salicifolia. J. Ethnopharmacol. 15(2), 161-167 (1986).