An internal standard for the quantification of dodecylphosphocholine
Related Products
Unlabeled Version(s)
25629Dodecylphosphocholine
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Dodecylphosphocholine-d38

Item No. 25996

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[[(dodecyl-d25-oxy)hydroxyphosphinyl]oxy]-N,N,N-tri(methyl-d3)-ethan-1,1,2,2-d4-aminium, inner salt
CAS Number
130890-78-7
Synonyms
  • n-Dodecylphosphocholine-d38
Molecular Formula
C17D38NO4P
Formula Weight
389.7
Purity
≥99% deuterated forms (d1-d38)
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 16 mg/mlDMSO: 16 mg/mlEthanol: 15 mg/mlPBS (pH 7.2): 25 mg/ml
SMILES
O=P(OC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])[2H])([O-])OC([2H])([2H])C([2H])([2H])[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]
InChi Code
InChI=1S/C17H38NO4P/c1-5-6-7-8-9-10-11-12-13-14-16-21-23(19,20)22-17-15-18(2,3)4/h5-17H2,1-4H3/i1D3,2D3,3D3,4D3,5D2,6D2,7D2,8D2,9D2,10D2,11D2,12D2,13D2,14D2,15D2,16D2,17D2
InChi Key
QBHFVMDLPTZDOI-DHIOKLJKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    25 mg

    $99

    Add

    50 mg

    $190

    Add

    100 mg

    $337

    Add

    250 mg

    $544

    Add
    Product Description

    Dodecylphosphocholine-d38 is intended for use as an internal standard for the quantification of dodecylphosphocholine (Item No. 25629) by GC- or LC-MS. Dodecylphosphocholine is a detergent that is commonly used for membrane protein structure determination using NMR.1 It has also been used to generate membrane mimetic micelles and to characterize pore formation by the influenza M2 transmembrane domain within a synthetic membrane.2 Dodecylphosphocholine micelles induce amyloid fibril formation by the prion protein (PrP) β-strand (PrP (110-136)).3 Dodecylphosphocholine has a critical micelle concentration (CMC) of approximately 1.5 mM.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kurauskas, V., Hessel, A., Ma, P., et al. How detergent impacts membrane proteins: Atomic-level views of mitochondrial carriers in dodecylphosphocholine. J. Phys. Chem. Lett. 9(5), 933-938 (2018).

    2. Cady, S.D., Wang, J., Wu, Y., et al. Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine micelles determined by NMR spectroscopy. J. Am Chem. Soc. 133(12), 4274-4284 (2011).

    3. Sauvé, S., and Aubin, Y. Dodecylphosphocholine micelles induce amyloid formation of the PrP(110-136) peptide via an α-helical metastable conformation. PLoS One 11(12), e0168021 (2016).