An esterified form of 5-oxoETE
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Alternative(s)
342505-OxoETE
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5-OxoETE methyl ester

Item No. 26059

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid, methyl ester
CAS Number
74785-00-5
Synonyms
  • 5-KETE methyl ester
Molecular Formula
C21H32O3
Formula Weight
332.5
Purity
≥95%
Formulation
A 100 µg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
0.1 M Na2CO3: 2 mg/mlDMF: miscibleDMSO: miscibleEthanol: misciblePBS (pH 7.2): 0.8 mg/ml
λmax
280 nm
SMILES
CCCCC/C=C\C/C=C\C/C=C\C=C\C(CCCC(OC)=O)=O
InChi Code
InChI=1S/C21H32O3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-17-20(22)18-16-19-21(23)24-2/h7-8,10-11,13-15,17H,3-6,9,12,16,18-19H2,1-2H3/b8-7-,11-10-,14-13-,17-15+
InChi Key
MOPVYNAAXAJXEV-IQTJLPEBSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    25 µg

    $104

    Add

    50 µg

    $195

    Add

    100 µg

    $368

    Add

    250 µg

    $813

    Add
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    Product Description

    5-OxoETE methyl ester is an esterified form of the polyunsaturated keto acid 5-oxoETE (Item No. 34250). 5-OxoETE methyl ester is an agonist of oxoeicosanoid receptor 1 (OXER1; EC50 = 1.54 µM for β-arrestin recruitment) that has a higher maximal response than 5-oxoETE in a β-arrestin assay.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Stepniewski, T.M., Torrens-Fontanals, M., Rodríguez-Espigares, I., et al. Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists. Bioorg. Med. Chem. 26(12), 3580-3587 (2018).