A semi-synthetic β-lactam antibiotic
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Ticarcillin (sodium salt)

Item No. 26065

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2S,5R,6R)-6-[[2-carboxy-2-(3-thienyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, disodium salt
CAS Number
4697-14-7
Molecular Formula
C15H14N2O6S2 • 2Na
Formula Weight
428.4
Purity
≥95% (mixture of diastereomers)
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 16 mg/mlEthanol: 2 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
302 nm
SMILES
CC1(C)[C@H](C([O-])=O)N2C([C@@H](NC(C(C([O-])=O)C3=CSC=C3)=O)[C@@]2([H])S1)=O.[Na+].[Na+]
InChi Code
InChI=1S/C15H16N2O6S2.2Na/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6;;/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23);;/q;2*+1/p-2/t7?,8-,9+,12-;;/m1../s1
InChi Key
ZBBCUBMBMZNEME-UBXQQCHXSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Ticarcillin is a semisynthetic β-lactam antibiotic.1,2 It is active against P. aeruginosa, E. coli, P. mirabilis, P. rettgeri, and K. aerogenes (MICs = 4-125 μg/ml).2 Topical administration of ticarcillin (2.5 mg per eye) reduces P. aeruginosa colony count in rabbit eye.1 Formulations containing ticarcillin have been used in the treatment of a variety of bacterial infections.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ahmad, A., Smolin, G., Okumoto, M., et al. Ticarcillin in the treatment of experimental pseudomonas keratitis. Br. J. Ophthalmol. 61(2), 92-95 (1977).

    2. Comber, K.R., Basker, M.J., Osborne, C.D., et al. Synergy between ticarcillin and tobramycin against Pseudomonas aeruginosa and Enterobacteriaceae in vitro and in vivo. Antimicrob. Agents Chemother. 11(6), 956-964 (1977).