A sterol
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

FF-MAS

Item No. 26093

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β,5α)-4,4-dimethyl-cholesta-8,14,24-trien-3-ol
CAS Number
64284-64-6
Synonyms
  • Follicular Fluid Meiosis-activating Sterol
Molecular Formula
C29H46O
Formula Weight
410.7
Purity
≥90%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly Soluble
SMILES
CC1(C)[C@@H](O)CC[C@@]2(C)[C@@]1([H])CCC3=C2CC[C@@]4(C)C3=CC[C@]4([H])[C@@H](CC/C=C(C)/C)C
InChi Code
InChI=1S/C29H46O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,13,20,22,25-26,30H,8,10-12,14-18H2,1-7H3/t20-,22-,25+,26+,28-,29-/m1/s1
InChi Key
LFQXEZVYNCBVDO-PBJLWWPKSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $1,293

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    Follicular fluid meiosis-activating sterol (FF-MAS) is an intermediate in cholesterol biosynthesis from lanosterol (Item No. 19521) that is found at high concentrations in mammalian ovarian follicular fluid.1 It increases survival of human oocytes isolated from patients with polycystic ovarian syndrome (PCOS) and improves cytoplasmic maturation of immature rodent and porcine oocytes in vitro.2 FF-MAS promotes completion of meiotic maturation to metaphase II and increases the rate of successful in vitro fertilization (IVF) in isolated mouse oocytes.3 Formulations containing FF-MAS have been used to improve embryo quality and implantation rate during IVF.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bergh, C., Loft, A., Lundin, K., et al. Chromosomal abnormality rate in human pre-embryos derived from in vitro fertilization cycles cultured in the presence of Follicular-Fluid Meiosis Activating Sterol (FF-MAS). Hum. Reprod. 19(9), 2109-2117 (2004).

    2. Faerge, I., Strejcek, F., Laurincik, J., et al. The effect of FF-MAS on porcine cumulus-oocyte complex maturation, fertilization and pronucleus formation in vitro. Zygote 14(3), 189-199 (2006).

    3. Marín Bivens, C.L., Lindenthal, B., O'Brien, M.J., et al. A synthetic analogue of meiosis-activating sterol (FF-MAS) is a potent agonist promoting meiotic maturation and preimplantation development of mouse oocytes maturing in vitro. Hum. Repod. 19(10), 2340-2344 (2004).