A saturated plant sterol
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Sitostanol

Item No. 26094

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(5α)-stigmastan-3β-ol
CAS Number
83-45-4
Synonyms
  • 24α-ethyl Cholestanol
  • NSC 49081
  • β-Sitostanol
  • Stigmastanol
Molecular Formula
C29H52O
Formula Weight
416.7
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly Soluble
SMILES
CC(C)[C@H](CC)CC[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C
InChi Code
InChI=1S/C29H52O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h19-27,30H,7-18H2,1-6H3/t20-,21-,22+,23+,24+,25-,26+,27+,28+,29-/m1/s1
InChi Key
LGJMUZUPVCAVPU-HRJGVYIJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    5 mg

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    10 mg

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    25 mg

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    Product Description

    Sitostanol is a saturated sterol found in a variety of plants, including corn, wheat, and rice.1 It reduces cholesterol uptake in isolated rat jejunal loops when used at a concentration of 0.3 mM in a micellar solution containing cholesterol.2 Sitostanol decreases liver cholesterol levels and prevents abdominal aorta atheroma in rabbits when administered in a cholesterol-containing diet at 0.5%.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Anderson, R.J., Nabsnhauer, F.P., and Shriner, R.L. The distribution of dihydrositosterol in plant fats. The Journal of Biological Chemisty 71, 389-399 (1927).

    2. Hassan, A.S., and Rampone, A.J. Effect of β-sitostanol (5 α-stigmastan-3 β-ol) on cholesterol absorption from micellar solutions in jejunal loops in situ. Steroids 36(6), 731-741 (1980).

    3. Ikeda, I., Kawasaki, A., Samezima, K., et al. Antihypercholesterolemic activity of β-sitostanol in rabbits. J. Nutr. Sci. Vitaminol. (Tokyo) 27(3), 243-251 (1981).