A VHL ligand 1 derivative
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VH 032 Linker 3 (hydrate)

Item No. 26151

Technical Information
Formal Name
(4R)-N-(5-amino-1-oxopentyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide, dihydrochloride, hydrate
Molecular Formula
C27H39N5O4S • 2HCl [XH2O]
Formula Weight
Purity
≥95%
A crystalline solid
DMSO: 50 mg/mlWater: 50 mg/ml
λmax
272 nm
SMILES
O=C([C@@H](NC(CCCCN)=O)C(C)(C)C)N1C[C@H](O)C[C@H]1C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O.Cl.Cl.O
InChi Code
InChI=1S/C27H39N5O4S.2ClH.H2O/c1-17-23(37-16-30-17)19-10-8-18(9-11-19)14-29-25(35)21-13-20(33)15-32(21)26(36)24(27(2,3)4)31-22(34)7-5-6-12-28;;;/h8-11,16,20-21,24,33H,5-7,12-15,28H2,1-4H3,(H,29,35)(H,31,34);2*1H;1H2/t20-,21+,24-;;;/m1.../s1
InChi Key
UUIYTMZCHFYYAE-PQFZTLBESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    VH 032 linker 3 is a derivative of the proteolysis-targeting chimera technology (PROTAC) building block VHL ligand 1 (Item No. 21591).

    WARNING This product is not for human or veterinary use.