A nucleotide
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Adenosine 3'-monophosphate (sodium salt hydrate)

Item No. 26256

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3'-adenylic acid, sodium salt, hydrate
Synonyms
  • 3’-AMP
Molecular Formula
C10H14N5O7P • XNa [XH2O]
Formula Weight
347.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
λmax
259 nm
SMILES
OC[C@@H]1[C@@H](OP(O)(O)=O)[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O1.[Na].O
InChi Code
InChI=1S/C10H14N5O7P.Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(17)7(4(1-16)21-10)22-23(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);;1H2/t4-,6-,7-,10-;;/m1../s1
InChi Key
BAKJBUWNNRHUHN-IDIVVRGQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    50 mg

    $49

    Add

    100 mg

    $86

    Add

    250 mg

    $202

    Add
    Product Description

    Adenosine 3'-monophosphate is a nucleotide and metabolite formed via hydrolysis of 2',3'-cAMP by metal-dependent phosphodiesterases.1 It reduces proliferation of rat preglomerular vascular smooth muscles cells (PGVSMCs) and glomerular mesangial cells (GMCs) in a concentration-dependent manner, an effect that is abolished by the adenosine A2B receptor antagonist MRS1754.2 Adenosine 3'-monophosphate is also a metabolic intermediate in the biosynthesis of adenosine (Item No. 21232).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Rao, F., Yaning, Q., Murugan, E., et al. 20,30-cAMP hydrolysis bymetal-dependent phosphodiesterases containing DHH, EAL, and HD domains is non-specific: Implications for PDE screening. Biochem. Bioph. Res. Commun. 398(3), 500-505 (2010).

    2. Jackson, E.K., Gillespie, D.G., and Dubey, R.K. 2'-AMP and 3'-AMP inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. J. Pharmacol. Exp. Ther. 337(2), 444-450 (2011).