An Analytical Reference Standard
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18625Betaxolol (hydrochloride)
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Betaxolol (hydrochloride)

Item No. 26285

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • SL 75212
Technical Information
Formal Name
1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol, monohydrochloride
CAS Number
63659-19-8
Molecular Formula
C18H29NO3 • HCl
Formula Weight
343.9
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 25 mg/mlEthanol: 25 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
224, 276 nm
SMILES
OC(CNC(C)C)COC1=CC=C(CCOCC2CC2)C=C1.Cl
InChi Code
InChI=1S/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3;1H
InChi Key
CHDPSNLJFOQTRK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Betaxolol (hydrochloride) (Item No. 26285) is an analytical reference standard categorized as a β1-adrenergic receptor antagonist.1 Formulations containing β-adrenergic receptor antagonists have been used to enhance physical performance in athletes.2,3 This product is intended for use in analytical forensic applications. This product is also available as a general research tool (Item No. 18625).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Baker, J.G. The selectivity of β-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptors. Br. J. Pharmacol. 144(3), 317-322 (2005).

    2. Myung, S.-W., and Jo, C.-H. Gas chromatograph-mass spectrometric method for the determination of carvedilol and its metabolites in human urine. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 822(1-2), 70-77 (2005).

    3. Gupta, P., and Goyal, R.N. Amino functionalized graphene oxide and polymer nanocomposite based electrochemical platform for sensitive assay of anti-doping drug atenolol in biological fluids. J. Electrochem. Soc. 163(13), B601-B608 (2016).