An Analytical Reference Standard
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15418Carvedilol
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Carvedilol

Item No. 26286

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • BM 14190
Technical Information
Formal Name
1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
CAS Number
72956-09-3
Molecular Formula
C24H26N2O4
Formula Weight
406.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS(pH 7.2) (1:4): 0.2 mg/mlEthanol: 5 mg/ml
λmax
224, 244, 286, 320, 333 nm
SMILES
COC1=C(OCCNCC(COC2=C(C(C=CC=C3)=C3N4)C4=CC=C2)O)C=CC=C1
InChi Code
InChI=1S/C24H26N2O4/c1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20/h2-12,17,25-27H,13-16H2,1H3
InChi Key
OGHNVEJMJSYVRP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Carvedilol (Item No. 26286) is an analytical reference standard categorized as a β-adrenergic receptor antagonist and vasodilator.1,2 Formulations containing carvedilol have been used to enhance physical performance in athletes.3 This product is intended for use in analytical forensic applications. This product is also available as a general research tool (Item No. 15418).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nichols, A.J., Sulpizio, A.C., Ashton, D.J., et al. In vitro pharmacologic profile of the novel beta-adrenoceptor antagonist and vasodilator, carvedilol. Pharmacology 39(5), 327-336 (1989).

    2. Bristow, M.R., Roden, R.I., Lowes, B.D., et al. The role of third-generation beta-blocking agents in chronic heart failure. Clin. Cardiol. 21(12 Suppl 1), I3-I13 (1998).

    3. Myung, S.-W., and Jo, C.-H. Gas chromatograph-mass spectrometric method for the determination of carvedilol and its metabolites in human urine. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 822(1-2), 70-77 (2005).