An Analytical Reference Standard
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16136Sotalol (hydrochloride)
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Sotalol (hydrochloride)

Item No. 26291

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • MJ1999
Technical Information
Formal Name
N-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-methanesulfonamide, monohydrochloride
CAS Number
959-24-0
Molecular Formula
C12H20N2O3S • HCl
Formula Weight
308.8
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
232 nm
SMILES
CS(NC1=CC=C(C(O)CNC(C)C)C=C1)(=O)=O.Cl
InChi Code
InChI=1S/C12H20N2O3S.ClH/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17;/h4-7,9,12-15H,8H2,1-3H3;1H
InChi Key
VIDRYROWYFWGSY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Sotalol (hydrochloride) (Item No. 26291) is an analytical reference standard categorized as a β-adrenergic receptor antagonist.1,2,3 It has been detected as an adverse analytical finding (AAF) during anti-doping testing.4 This product is intended for use in analytical forensic applications. This product is also available as a general research tool (Item No. 16136).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Antonaccio, M.J., and Gomoll, A. Pharmacology, pharmacodynamics and pharmacokinetics of sotalol. Am. J. Cardiol. 65(2), 12A-21A (1990).

    2. Tsuchihashi, H., Nakashima, Y., Kinami, J., et al. Characteristics of 125I-iodocyanopindolol binding to β-adrenergic and serotonin-1B receptors of rat brain: Selectivity of β-adrenergic agents. Jpn. J. Pharmacol. 52(2), 195-200 (1990).

    3. Baker, J.G. The selectivity of β-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptors. Br. J. Pharmacol. 144(3), 317-322 (2005).

    4. Agency, W.A.-D. 2014 Anti-doping testing figures report. (2014).