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Dorzolamide (hydrochloride)

Item No. 26303

Synonyms
Synonyms
  • L-671,152
  • MK-507
Technical Information
Formal Name
(4S,6S)-4-(ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide, 7,7-dioxide, monohydrochloride
CAS Number
130693-82-2
Molecular Formula
C10H16N2O4S3 • HCl
Formula Weight
Purity
≥98%
Formulation
A crystalline solid
PBS (pH 7.2): 1 mg/ml
λmax
255 nm
SMILES
O=S1([C@@H](C)C[C@H](NCC)C2=C1SC(S(N)(=O)=O)=C2)=O.Cl
InChi Code
InChI=1S/C10H16N2O4S3.ClH/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16;/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16);1H/t6-,8-;/m0./s1
InChi Key
OSRUSFPMRGDLAG-QMGYSKNISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Dorzolamide (hydrochloride) (Item No. 26303) is an analytical reference standard categorized as a carbonic anhydrase inhibitor diuretic.1 Diuretics have been used in sports doping to reduce weight or anabolic androgenic steroid-induced water retention, or as masking agents.2 This product is intended for use in analytical forensic applications. This product is also available as a general research tool (Item No. 14616).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Mottram, D.R. Diuretics and other masking agents. Drugs in Sport 121-131 (2011).

    2. Morra, V., Davit, P., Capra, P., et alFast gas chromatographic/mass spectrometric determination of diuretics and masking agents in human urine: Development and validation of a productive screening protocol for antidoping analysis. J. Chromatogr. A 1135(2), 219-229 (2006).