A resveratrol derivative with diverse biological activities
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Acetyl Resveratrol

Item No. 26379

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-[(1E)-2-[4-(acetyloxy)phenyl]ethenyl]-1,3-benzenediol, 1,3-diacetate
CAS Number
42206-94-0
Synonyms
  • Resveratrol triacetate
  • Triacetylresveratrol
  • 3,5,4'-Tri-O-acetylresveratrol
Molecular Formula
C20H18O6
Formula Weight
354.4
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 50 mg/mlDMSO: 50 mg/mlEthanol: 50 mg/mlPBS (pH 7.2): >0.1mg/ml
λmax
224, 300, 310 nm
SMILES
CC(OC(C=C1)=CC=C1/C=C/C2=CC(OC(C)=O)=CC(OC(C)=O)=C2)=O
InChi Code
InChI=1S/C20H18O6/c1-13(21)24-18-8-6-16(7-9-18)4-5-17-10-19(25-14(2)22)12-20(11-17)26-15(3)23/h4-12H,1-3H3/b5-4+
InChi Key
PDAYUJSOJIMKIS-SNAWJCMRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 mg

    $63

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    1 g

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    5 g

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    Cayman Chemical
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    Product Description

    Acetyl resveratrol is a triacetylated derivative of resveratrol that has diverse biological activities, including anticancer and antioxidant properties.1,2,3 It inhibits the growth of LNCaP, DU145, and PC3M prostate cancer cells (IC50s = 10.5, 14.2, and 26.8 μM, respectively).2 Acetyl resveratrol induces cytotoxicity in ALL-5 acute lymphoblastic leukemia cells (IC50 = 3.4 μM) and induces cell cycle arrest at the G1 phase when used at a concentration of 17 μM.1 It also increases survival in mice exposed to total body γ-irradiation when administered at a dose of 10 mg/kg prior to irradiation.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Urbaniak, A., Delgado, M., Kacprzak, K., et al. Activity of resveratrol triesters against primary acute lymphoblastic leukemia cells. Bioor. Med. Chem. Lett. 27(12), 2766-2770 (2017).

    2. Dias, S.J., Li, K., Rimando, A.M., et al. Trimethoxy-resveratrol and piceatannol administered orally suppress and inhibit tumor formation and growth in prostate cancer xenografts. Prostate 73(11), 1135-1146 (2016).

    3. Koide, K., Osman, S., Garner, A.L., et al. The use of 3,5,4'-Tri-O-acetylresveratrol as a potential pro-drug for resveratrol protects mice from γ-irradiation-induced death. ACS Med. Chem. Lett. 2(4), 270-274 (2011).