A steroidal alkaloid
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Peimisine (hydrochloride)

Item No. 26438

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2'R,3S,3'R,3'aS,4aS,6'S,6aR,6bS,7'aR,11aS,11bR)-1,2,3,3'a,4,4',4a,5',6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-5(6H)-one, monohydrochloride
CAS Number
900498-44-4
Molecular Formula
C27H41NO3 • HCl
Formula Weight
464.1
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: 16 mg/mlEthanol: 1 mg/mlPBS (pH 7.2): Partially soluble
λmax
204 nm
SMILES
O=C1[C@@]2([H])C[C@@H](O)CC[C@]2(C)[C@]3([H])[C@@]([C@@]4([H])C(C3)=C(C)[C@@]5(O[C@@](C[C@H](C)CN6)([H])[C@]6([H])[C@H]5C)CC4)([H])C1.Cl
InChi Code
InChI=1S/C27H41NO3.ClH/c1-14-9-24-25(28-13-14)16(3)27(31-24)8-6-18-19(15(27)2)11-21-20(18)12-23(30)22-10-17(29)5-7-26(21,22)4;/h14,16-18,20-22,24-25,28-29H,5-13H2,1-4H3;1H/t14-,16+,17-,18+,20-,21-,22+,24+,25-,26+,27-;/m0./s1
InChi Key
BVYFGCQMQQGAEY-MCZYSGEJSA-N
Origin
Plant/Fritillaria hupehensis Hsiao et K.C. Hsia
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $90

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    10 mg

    $158

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    25 mg

    $349

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    50 mg

    $609

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    Product Description

    Peimisine is a steroidal alkaloid originally isolated from Fritillaria.1 It inhibits rabbit lung acetylcholinesterase (AChE) by 20.2% when used at a concentration of 200 μM.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. An, J.-J., Zhou, J.-L., Li, H.-J., et al. Puqienine E: An angiotensin converting enzyme inhibitory steroidal alkaloid from Fritillaria puqiensis. Fitoterapia 81(3), 149-152 (2010).