An internal standard for the quantification of levetiracetam
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Unlabeled Version(s)
9001820Levetiracetam
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Levetiracetam-d6

Item No. 26457

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
αS-α-ethyl-5-oxo-1-pyrrolidine-2,2,3,3,4,4-d6-acetamide
CAS Number
1133229-30-7
Synonyms
  • (S)-Levetiracetam-d6
Molecular Formula
C8H8D6N2O2
Formula Weight
176.2
Purity
≥99% deuterated forms (d1-d6)
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Acetone: slightly soluble, sonicatedChloroform: slightly soluble
SMILES
NC([C@H](CC)N1C(C([2H])([2H])C([2H])([2H])C1([2H])[2H])=O)=O
InChi Code
InChI=1S/C8H14N2O2/c1-2-6(8(9)12)10-5-3-4-7(10)11/h6H,2-5H2,1H3,(H2,9,12)/t6-/m0/s1/i3D2,4D2,5D2
InChi Key
HPHUVLMMVZITSG-QXMLZOKMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $358

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    Product Description

    Levetiracetam-d6 is intended for use as an internal standard for the quantification of levetiracetam (Item No. 9001820) by GC- or LC-MS. Levetiracetam is an antiepileptic agent that binds to the synaptic vesicle protein SV2A (IC50 = 1.99 μM).1 In vivo, levetiracetam suppresses seizures in fully kindled rats.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lynch, B.A., Lamberg, N., Nocka, K., et al. The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proc. Natl. Acad. Sci. USA 101(26), 9861-9866 (2004).

    2. Löscher, W., and Brandt, C. Prevention or modification of epileptogenesis after brain insults: Experimental approaches and translational research. Pharmacol. Rev. 62(4), 668-700 (2010).