A cholesterol ester
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Cholesteryl Dihomo-γ-Linolenate

Item No. 26469

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
cholest-5-en-3β-ol, 3-(8Z,11Z,14Z)-8,11,14-eicosatrienoate
CAS Number
7274-08-0
Synonyms
  • 20:3 (8Z,11Z,14Z) CE
  • 20:3 n-6 CE
  • 20:3 (8Z,11Z,14Z) Cholesterol Ester
Molecular Formula
C47H78O2
Formula Weight
675.1
Purity
≥98%
Formulation (Request formulation change)
A 10 mg/ml solution in chloroform
Solubility(Learn about Variance in Solubility)
Chloroform: 10 mg/ml
SMILES
C[C@]12C(C[C@@H](OC(CCCCCC/C=C\C/C=C\C/C=C\CCCCC)=O)CC2)=CC[C@]3([H])[C@]1([H])CC[C@@]4(C)[C@@]3([H])CC[C@@]4([C@@H](CCCC(C)C)C)[H]
InChi Code
InChI=1S/C47H78O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-27-45(48)49-40-32-34-46(5)39(36-40)28-29-41-43-31-30-42(38(4)26-24-25-37(2)3)47(43,6)35-33-44(41)46/h11-12,14-15,17-18,28,37-38,40-44H,7-10,13,16,19-27,29-36H2,1-6H3/b12-11-,15-14-,18-17-/t38-,40+,41+,42-,43+,44+,46+,47-/m1/s1
InChi Key
MLPRJPSMAFZPLA-BBFGHUFCSA-N
Origin
Plant/Borago officinalis
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $36

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    5 mg

    $153

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    10 mg

    $268

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    25 mg

    $587

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    Product Description

    Cholesteryl dihomo-γ-linolenate is a cholesterol ester. It accumulates in the adrenal gland of rabbits fed a diet high in linolenic acid.1 Levels of cholesteryl dihomo-γ-linolenate are decreased and positively correlate with cognitive decline in HIV-infected humans.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Moore, J.H., and Williams, D.L. Dietary linoleic acid and the accumulation of homo-gamma-linolenic acid in the cholesterol esters of the adrenal gland of the rabbit. Biochim. Biophys. Acta 116(1), 181-183 (1966).

    2. Bandaru, V.V., Mielke, M.M., Sacktor, N., et al. A lipid storage-like disorder contributes to cognitive decline in HIV-infected subjects. Neurology 81(17), 1492-1499 (2013).