A cholesterol ester
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Cholesteryl Lignocerate

Item No. 26470

Technical Information
Formal Name
cholest-5-en-(3β)-ol, 3-tetracosanoate
CAS Number
73024-96-1
Synonyms
  • 24:0 CE
  • 24:0 Cholesterol ester
Molecular Formula
C51H92O2
Formula Weight
Purity
≥98%
A solid
Chloroform: 10 mg/ml
SMILES
C[C@]12C(C[C@@H](OC(CCCCCCCCCCCCCCCCCCCCCCC)=O)CC2)=CC[C@]3([H])[C@]1([H])CC[C@@]4(C)[C@@]3([H])CC[C@@]4([C@@H](CCCC(C)C)C)[H]
InChi Code
InChI=1S/C51H92O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-27-31-49(52)53-44-36-38-50(5)43(40-44)32-33-45-47-35-34-46(42(4)30-28-29-41(2)3)51(47,6)39-37-48(45)50/h32,41-42,44-48H,7-31,33-40H2,1-6H3/t42-,44+,45+,46-,47+,48+,50+,51-/m1/s1
InChi Key
AMUHTLRUMQYZJF-LTRCVRFVSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Cholesteryl lignocerate is a cholesterol ester that has been found in human meibum.1 Cholesteryl lignocerate can be hydrolyzed by cellular extracts from cultured human skin fibroblasts isolated from healthy individuals but not patients with cholesteryl ester storage disease (CESD) or Wolman disease.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chen, J., Green, K.B., and Nichols, K.K. Quantitative profiling of major neutral lipid classes in human meibum by direct infusion electrospray ionization mass spectrometry. Invest. Ophthalmol. Vis. Sci. 54(8), 5730-5753 (2013).

    2. Michels, V.V., and Beaudet, A.L. Cholesteryl lignocerate hydrolysis in adrenoleukodystrophy. Pediatr. Res. 14(1), 21-23 (1980).