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2-methyl AP-237 (hydrochloride)

Item No. 26485

Restricted Product (Schedule I)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 2-methyl Buccinazine
Technical Information
Formal Name
1-[2-methyl-4-(3-phenyl-2-propen-1-yl)-1-piperazinyl]-1-butanone, monohydrochloride
CAS Number
98608-59-4
Molecular Formula
C18H26N2O • HCl
Formula Weight
322.9
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 15 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
254 nm
SMILES
CCCC(N1CCN(C/C=C/C2=CC=CC=C2)CC1C)=O.Cl
InChi Code
InChI=1S/C18H26N2O.ClH/c1-3-8-18(21)20-14-13-19(15-16(20)2)12-7-11-17-9-5-4-6-10-17;/h4-7,9-11,16H,3,8,12-15H2,1-2H3;1H/b11-7+;
InChi Key
GPYVJSNBBPAWLD-RVDQCCQOSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

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    Cayman Chemical
    Cayman Spectral Library

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    Product Description

    2-methyl AP-237 (hydrochloride) (Item No. 26485) is an analytical reference standard categorized as an opioid.1 2-methyl AP-237 has been associated with fatal overdose.2 This product is intended for research and forensic applications.

    For more information, please see Cayman's 2-methyl AP-237 metabolism monograph..

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Vandeputte, M.M., Cannaert, A., and Stove, C.P. In vitro functional characterization of a panel of non‑fentanyl opioid new psychoactive substances. Arch. Toxicol. 94(11), 3819-3830 (2020).

    2. Truver, M.T., Crosby, M.M., Gillette, A.T., et al. Fatal intoxication involving 2-methyl AP-237. J. Forensic Sci. 68(4), 1419-1424 (2023).

    Product Citations

    Gerona, R., Ellison, R., and Trecki, J. DEA-TOX: Alert Regarding 2-Methyl AP-237– June 11, 2021. (2021).

    Vandeputte, M.M., Cannaert, A., and Stove, C.P. In vitro functional characterization of a panel of non‑fentanyl opioid new psychoactive substances. Arch. Toxicol. 94(11), 3819-3830 (2020).

    Krotulski, A.J., Fogarty, M.F., and Logan, B.K. 2-Methyl AP-237. 1-9 (2019).