A metabolite of prednisolone
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Parent Compound(s)
20866Prednisolone
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20α-dihydro Prednisolone

Item No. 26502

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
11β,17,20R,21-tetrahydroxy-pregna-1,4-dien-3-one
CAS Number
15847-24-2
Synonyms
  • 20α-DHP
  • 20α-dihydro-PRED
  • 20(R)-hydroxy Prednisolone
  • 20α-hydroxy Prednisolone
Molecular Formula
C21H30O5
Formula Weight
362.5
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: slightly solubleMethanol: slightly soluble
SMILES
[H][C@]12[C@@]([C@@](CC[C@]3(O)[C@H](O)CO)([H])[C@]3(C)C[C@@H]2O)([H])CCC4=CC(C=C[C@@]41C)=O
InChi Code
InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-18,22,24-26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,17+,18+,19-,20-,21-/m0/s1
InChi Key
LCOVYWIXMAJCDS-LCGKLAOVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

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    Product Description

    20α-dihydro Prednisolone is a metabolite of prednisolone (Item No. 20866).1,2 It has been found in the urine of cattle following adrenocorticotropic hormone (ACTH) administration but not in naturally stressed or non-stressed cattle.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Rodchenkov, G.M., Vedenin, A.N., Uralets, V.P., et al. Characterization of prednisone, prednisolone and their metabolites by gas chromatography-mass spectrometry. J. Chromatogr. 565(1-2), 45-51 (1991).

    2. Matabosch, X., Pozo, O.J., Pérez-Mañá, C., et al. Detection and characterization of prednisolone metabolites in human urine by LC-MS/MS. J. Mass. Spectrom. 50(3), 633-642 (2015).

    3. De Clercq, N., Van Meulebroek, L., Vanden Bussche, J., et al. The impact of stress on the prevalence of prednisolone in bovine urine: A metabolic fingerprinting approach. J. Steroid. Biochem. Mol. Biol. 154, 206-216 (2015).