An Analytical Reference Standard
Related Products
Active Metabolite(s)
15887DiazepamISO60177Diazepam (CRM)
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Avizafone (hydrochloride)

Item No. 26527

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • Prodiazepam
Technical Information
Formal Name
L-lysyl-N-(2-benzoyl-4-chlorophenyl)-N-methyl-glycinamide, dihydrochloride
CAS Number
60067-16-5
Molecular Formula
C22H27ClN4O3 • 2HCl
Formula Weight
503.9
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/mlPBS pH 7.2: Soluble: ≥10 mg/ml
SMILES
O=C(C1=CC(Cl)=CC=C1N(C(CNC([C@@H](N)CCCCN)=O)=O)C)C2=CC=CC=C2.Cl.Cl
InChi Code
InChI=1S/C22H27ClN4O3.2ClH/c1-27(20(28)14-26-22(30)18(25)9-5-6-12-24)19-11-10-16(23)13-17(19)21(29)15-7-3-2-4-8-15;;/h2-4,7-8,10-11,13,18H,5-6,9,12,14,24-25H2,1H3,(H,26,30);2*1H/t18-;;/m0../s1
InChi Key
OVKGTIITDUZFJC-NTEVMMBTSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Avizafone (hydrochloride) (Item No. 26527) is an analytical reference standard categorized as a prodrug form of diazepam (Item Nos. ISO60177 | 15887).1,2 Formulations containing avizafone have been used as antidotes for nerve agent exposure in a military setting. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hassall, C.H., Wolmes, S.W., Johnson, W.H., et al. Peptido-aminobenzophenones-novel latentiated benzo-1,4-diazepines. Experientia 33(11), 1492-1493 (1977).

    2. Price, M.E., Whitmore, C.L., Tattersall, J.E.H., et al. Efficacy of the antinicotinic compound MB327 against soman poisoning - Importance of experimental end point. Toxicol. Lett. 293, 167-171 (2018).