A fluorescent H2S probe
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CAY10731

Item No. 26548

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
carbonic acid, 2-bromoethyl 6'-methoxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl ester
CAS Number
2119597-33-8
Molecular Formula
C24H17BrO7
Formula Weight
497.3
Purity
≥95%
Emission
535 nm
Excitation
485 nm
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/ml
λmax
223, 274 nm
SMILES
COC(C=C1)=CC2=C1C3(C(C=CC=C4)=C4C(O3)=O)C(C=CC(OC(OCCBr)=O)=C5)=C5O2
InChi Code
InChI=1S/C24H17BrO7/c1-28-14-6-8-18-20(12-14)31-21-13-15(30-23(27)29-11-10-25)7-9-19(21)24(18)17-5-3-2-4-16(17)22(26)32-24/h2-9,12-13H,10-11H2,1H3
InChi Key
XOUSDCPPGSMKQF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $49

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    5 mg

    $202

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    10 mg

    $329

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    25 mg

    $702

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    Product Description

    CAY10731 is a fluorescent probe for hydrogen sulfide (H2S).1 Upon reaction with H2S, fluorescein (FITC) is released and its fluorescence can be used to detect H2S. FITC displays excitation/emission maxima of 485/535 nm, respectively. CAY10731 is selective for H2S over glutathione (GSH), cysteine, H2O3-, SO3-, and H2O2 as well as tBuO and OH radicals. It has been used to detect H2S in rat hippocampal slices and nematodes.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Reja, S.I., Sharma, N., Gupta, M., et al. A highly selective fluorescent probe for detection of hydrogen sulfide in living systems: In vitro and in vivo applications. Chemistry 23(41), 9872-9878 (2017).

    Product Citations

    Zhou, Y., Mazur, F., Liang, K., et al. Sensitivity and selectivity analysis of fluorescent probes for hydrogen sulfide detection. Chem. Asian J. 17(5), e202101399 (2022).