A clickable form of stearic acid
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Unmodified Version(s)
10011298Stearic Acid
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18-azido Stearic Acid

Item No. 26693

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
18-azido-octadecanoic acid
CAS Number
1529763-58-3
Synonyms
  • C18:0 Azide
  • FA 18:0 Azide
  • Octadecanoic Acid Azide
  • ω-azido Stearate
Molecular Formula
C18H35N3O2
Formula Weight
325.5
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/mlEthanol: Slightly soluble: 0.1-1 mg/ml
SMILES
O=C(CCCCCCCCCCCCCCCCCN=[N+]=[N-])O
InChi Code
InChI=1S/C18H35N3O2/c19-21-20-17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-18(22)23/h1-17H2,(H,22,23)
InChi Key
CWGJPRJZWKUHEV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $79

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    10 mg

    $126

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    25 mg

    $237

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    50 mg

    $395

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    Product Description

    18-azido Stearic acid is a clickable form of stearic acid (Item No. 10011298) functionalized with azide, which reacts with alkynes, such as dibenzocyclooctyne (DBCO), to form a stable conjugate.1 It has been used as a probe to study S-acylation by zinc finger DHHC domain-containing (zDHHC) palmitoyltransferases in vitro.2 18-azido Stearic acid has also been used as a building block in the synthesis of a Cy7-labeled lysophosphatidylcholine (LPC) derivative to evaluate brain tumor penetration in an orthotopic GL261 murine glioma model.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yu, J., Tu, Z., Fan, J., et al. Phosphatidylcholine-derived carriers facilitate brain tumor delivery and enhance glioblastoma therapy. J. Control. Release 385:113999, (2025).

    2. Greaves, J., Munro, K.R., Davidson, S.C., et al. Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry. Proc. Natl. Acad. Sci. USA 114(8), E1365-E1374 (2017).