An internal standard for the quantification of L-carnosine
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Unlabeled Version(s)
29825L-Carnosine
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L-Carnosine-d4

Item No. 26781

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3-aminopropanoyl-2,2,3,3-d4)-L-histidine
CAS Number
2714339-90-7
Synonyms
  • β-Alanyl-L-histidine-d4
Molecular Formula
C9H10D4N4O3
Formula Weight
230.3
Purity
≥99% deuterated forms (d1-d4)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/mlWater: Slightly soluble
SMILES
OC([C@@H](NC(C([2H])([2H])C([2H])([2H])N)=O)CC1=CN=CN1)=O
InChi Code
InChI=1S/C9H14N4O3/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6/h4-5,7H,1-3,10H2,(H,11,12)(H,13,14)(H,15,16)/t7-/m0/s1/i1D2,2D2
InChi Key
CQOVPNPJLQNMDC-IMRHFWKNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $132

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    1 mg

    $251

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    Product Description

    L-Carnosine-d4 is intended for use as an internal standard for the quantification of L-carnosine by GC- or LC-MS. L-Carnosine is an antioxidant.1,2 It scavenges singlet oxygen in vitro when used at concentrations ranging from 1.5 to 15 mM.1 In vivo, L-carnosine decreases plasma malondialdehyde (MDA) levels and lipid peroxidation and increases serum levels of nitric oxide (NO) in nephrectomized rats.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hartman, P.E., Hartman, Z., and Ault, K.T. Scavenging of singlet molecular oxygen by imidazole compounds: High and sustained activities of carboxy terminal histidine dipeptides and exceptional activity of imidazole-4-acetic acid. Photochem. Photobiol. 51(1), 59-66 (1990).

    2. Yapislar, H., and Taskin, E. L-carnosine alters some hemorheologic and lipid peroxidation parameters in nephrectomized rats. Med. Sci. Monit. 20, 399-405 (2014).