An internal standard for the quantification of sulfamethizole
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Unlabeled Version(s)
23355Sulfamethizole
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Sulfamethizole-d4

Item No. 26789

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzene-d4-sulfonamide
CAS Number
2470130-12-0
Synonyms
  • N1-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide-d4
Molecular Formula
C9H6D4N4O2S2
Formula Weight
274.3
Purity
≥99% deuterated forms (d1-d4)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: slightly solubleMethanol: slightly soluble
SMILES
NC1=C([2H])C([2H])=C(S(NC2=NN=C(C)S2)(=O)=O)C([2H])=C1[2H]
InChi Code
InChI=1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)/i2D,3D,4D,5D
InChi Key
VACCAVUAMIDAGB-QFFDRWTDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Cayman Chemical
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    Product Description

    Sulfamethizole-d4 is intended for use as an internal standard for the quantification of sulfamethizole (Item No. 23355) by GC- or LC-MS. Sulfamethizole is a broad-spectrum sulfonamide antibiotic (MIC90s = 1.25-5,000 µg/ml against clinical isolates of E. coli and K. pneumoniae).1 It inhibits dihydropteroate synthase, an enzyme involved in folate biosynthesis. Formulations containing sulfamethizole have previously been used to treat urinary tract infections.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wambaugh, M.A., Shakya, V.P.S., Lewis, A.J., et al. High-throughput identification and rational design of synergistic small-molecule pairs for combating and bypassing antibiotic resistance. PLoS Biol. 15(6):e2001644, (2017).