A fluorogenic substrate for C8 esterase
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4-Methylumbelliferyl Caprylate

Item No. 26802

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
octanoic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester
CAS Number
20671-66-3
Synonyms
  • MUCAP
  • 4-MU Caprylate
Molecular Formula
C18H22O4
Formula Weight
302.4
Purity
≥98%
Emission
445 to 455 nm, increasing as pH decreases
Excitation
320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly soluble: 0.1-1 mg/mLChloroform: soluble
SMILES
O=C1C=C(C)C2=C(C=C(OC(CCCCCCC)=O)C=C2)O1
InChi Code
InChI=1S/C18H22O4/c1-3-4-5-6-7-8-17(19)21-14-9-10-15-13(2)11-18(20)22-16(15)12-14/h9-12H,3-8H2,1-2H3
InChi Key
WZEWYQWWSCVHCP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

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    Product Description

    4-Methylumbelliferyl caprylate (MUCAP) is a fluorogenic substrate for C8 esterase.1 MUCAP is cleaved by C8 esterase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Manafi, M. Fluorogenic and chromogenic enzyme substrates in culture media and identification tests. Int. J. Food Microbiol. 31(1-3), 45-58 (1996).

    2. Zhi, H., Wang, J., Wang, S., et al. Fluorescent properties of hymecromone and fluorimetric analysis of hymecromone in compound dantong capsule. J. Spectrosc. 147128 (2013).