A fluorescent probe
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9-Anthryldiazomethane

Item No. 26806

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9-(diazomethyl)-anthracene
CAS Number
10401-59-9
Molecular Formula
C15H10N2
Formula Weight
218.3
Purity
≥85%
Emission
412 nm
Excitation
365 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
λmax
255 nm
SMILES
[N-]=[N+]=CC1=C(C=CC=C2)C2=CC3=C1C=CC=C3
InChi Code
InChI=1S/C15H10N2/c16-17-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)15/h1-10H
InChi Key
XXDVOJKRZBNPFN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

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    Product Description

    9-Anthryldiazomethane is a fluorescent probe that has been used for the detection of fatty acids, arachidonic acid metabolites, prostaglandins, leukotrienes, and thromboxanes.1 It reacts with carboxylic acid groups and produces a fluorescent ester that can be detected via HPLC. 9-Anthryldiazomethane displays excitation/emission maxima of 365/412 nm in 80:20 solutions of acetonitrile:water and methanol:water.2 It has also been used to detect amino acids via HPLC with excitation/emission maxima of 255/412 nm, respectively.3 9-Anthryldiazomethane has been used as a synthetic intermediate in the synthesis of anthracene-containing polymers.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Murphy, T.H., Malouf, A.T., Sastre, A., et al. Calcium-dependent glutamate cytotoxicity in a neuronal cell line. Brain Res. 444(2), 325-332 (1988).

    2. Nimura, N., and Kinoshita, T. Fluorescent labeling of fatty acids with 9-anthryldiazomethane (ADAM) for high performance liquid chromatography. Analyt. Lett. 13(A3), 191-202 (1980).

    3. Yoshida, T., Uetake, A., Murayama, H., et al. Fluorescent labelling of amino acids with 9-anthryldiazomethane and its applications to high-performance liquid chromatography. J. Chromatogr. A 348(2), 425-429 (1985).

    4. Krakovyak, M.G., Anufrieva, E.V., Lushchik, V.B., et al. 9-Anthryldiazomethane in the synthesis of anthracene-containing polymers. J. Macromol. Sci. A12(6), 789-814 (1978).