A diacylglycerol
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1,3-Dipalmitoyl Glycerol

Item No. 26974

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
hexadecanoic acid, 1,1'-(2-hydroxy-1,3-propanediyl) ester
CAS Number
502-52-3
Synonyms
  • DG(16:0/0:0/16:0)
  • 1,3-Dipalmitin
Molecular Formula
C35H68O5
Formula Weight
568.9
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 30 mg/mlEthanol: 0.25 mg/mlPBS (pH 7.2): 0.7 mg/ml
SMILES
OC(COC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O
InChi Code
InChI=1S/C35H68O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(37)39-31-33(36)32-40-35(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h33,36H,3-32H2,1-2H3
InChi Key
GFAZGHREJPXDMH-UHFFFAOYSA-N
Side Chain Carbon Sum
32:0
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    250 mg

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    Product Description

    1,3-Dipalmitoyl glycerol is a diacylglycerol that contains palmitic acid (Item No. 10006627) at the sn-1 and sn-3 positions. It activates protein kinase C α (PKCα) in vitro (Ka = 3.8 μM).1 1,3-Dipalmitoyl glycerol (0.25-2 μM) inhibits apoptosis and production of reactive oxygen species (ROS) and pro-inflammatory mediators induced by oxygen-glucose deprivation and reperfusion (OGD/R) in SH-SY5Y neuroblastoma cells.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sánchez-Piñera, P., Micol, V., Corbalán-García, S., et al. A comparative study of the activation of protein kinase C α by different diacylglycerol isomers. Biochem. J. 337(3), 387-395 (1999).

    2. Cheng, M.-C., and Pan, T.-M. Glyceryl 1,3-dipalmitate produced from Lactobacillus paracasei subspecies. paracasei NTU 101 inhibits oxygen-glucose deprivation and reperfusion-induced oxidative stress via upregulation of peroxisome proliferator-activated receptor γ in neuronal SH-SY5Y cells. J. Agric. Food Chem. 65(36), 7926-7933 (2017).