A turn-on fluorescent probe for carbon monoxide
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CAY10737

Item No. 27026

Technical Information
Formal Name
2-[2-[2,3-dihydro-6-[[(2-propen-1-yloxy)carbonyl]oxy]-1H-xanthen-4-yl]ethenyl]-1,3,3-trimethyl-3H-indolium
CAS Number
2079118-42-4
Molecular Formula
C30H30NO4
Formula Weight
Purity
≥95%
Emission
714 nm
A crystalline solid
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 1 mg/ml
λmax
240, 306, 345, 589 nm
SMILES
C[N+]1=C(C(C)(C)C2=C1C=CC=C2)/C=C/C(CCC3)=C(C3=C4)OC5=C4C=CC(OC(OCC=C)=O)=C5
InChi Code
InChI=1S/C30H30NO4/c1-5-17-33-29(32)34-23-15-13-21-18-22-10-8-9-20(28(22)35-26(21)19-23)14-16-27-30(2,3)24-11-6-7-12-25(24)31(27)4/h5-7,11-16,18-19H,1,8-10,17H2,2-4H3/q+1/b16-14+
InChi Key
JRXRMPWUNYRPST-JQIJEIRASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    Product Description

    CAY10737 is a turn-on fluorescent probe for the detection of carbon monoxide (CO).1 It is selective for CO over a variety of anions, amino acids, amines, biothiols, and reactive species. In the presence of palladium (Pd) and CO, CAY10737 undergoes the Pd0-mediated Tsuji-Trost reaction to release a fluorescent compound that has absorption and emission maxima of 678/714 nm, respectively. This fluorescence can be used to detect CO production in vitro and in vivo. CAY10737 has low cytotoxicity, decreasing viability of HeLa cells by less than 25% when used at a concentration of 50 µM with PdCl2 for 24 hours.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Feng, W., and Feng, H. A readily available colorimetric and near-infrared fluorescent turn-on probe for detection of carbon monoxide in living cells and animals. Sens. Actuators B Chem. 255(Part 2), 2314-2320 (2018).