An antiprotozoal agent
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Imidocarb (propionate)

Item No. 27053

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N,N'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea, dipropanoate
CAS Number
55750-06-6
Molecular Formula
C19H20N6O • 2C3H6O2
Formula Weight
496.6
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlDMSO: 1 mg/mlEthanol: 1 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
220, 260 nm
SMILES
O=C(NC1=CC=CC(C2=NCCN2)=C1)NC3=CC(C4=NCCN4)=CC=C3.OC(CC)=O.OC(CC)=O
InChi Code
InChI=1S/C19H20N6O.2C3H6O2/c26-19(24-15-5-1-3-13(11-15)17-20-7-8-21-17)25-16-6-2-4-14(12-16)18-22-9-10-23-18;2*1-2-3(4)5/h1-6,11-12H,7-10H2,(H,20,21)(H,22,23)(H2,24,25,26);2*2H2,1H3,(H,4,5)
InChi Key
AFGQXWSHYUHHNV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
4°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Cayman Chemical
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    Product Description

    Imidocarb is an antiprotozoal agent.1 It is active against the protozoan parasite B. bovis (IC50 = 0.87 µg/ml).2 Imidocarb (1.2 mg/kg) eliminates parasites in blood in a splenectomized lamb model of B. ovis infection and increases survival when administered at a dose of 2.4 mg/kg prior to infection.3 Formulations containing imidocarb have been used in the veterinary treatment of babesiosis and other protozoal infections.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Mosqueda, J., Olvera-Ramírez, A., Aguilar-Tipacamú, G., et al. Current advances in detection and treatment of babesiosis. Curr. Med. Chem. 19(10), 1504-1518 (2012).

    2. Rodriguez, R.I., and Trees, A.J. In vitro responsiveness of Babesia bovis to imidocarb dipropionate and the selection of a drug-adapted line. Vet. Parasitol. 62(1-2), 35-41 (1996).

    3. Sevinc, F., Turgut, K., Sevinc, M., et al. Therapeutic and prophylactic efficacy of imidocarb dipropionate on experimental Babesia ovis infection of lambs. Vet. Parasitol. 149(1-2), 65-71 (2007).