An amino monosaccharide
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D-Glucosamine (hydrochloride)

Item No. 27055

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-amino-2-deoxy-D-glucose, monohydrochloride
CAS Number
66-84-2
Synonyms
  • D-(+)-Glucosamine
  • GlcN
  • NSC 234443
  • NSC 758
Molecular Formula
C6H13NO5 • HCl
Formula Weight
215.6
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
SMILES
N[C@H]([C@@H](O)[C@H](O)[C@H](O)CO)C=O.Cl
InChi Code
InChI=1S/C6H13NO5.ClH/c7-3(1-8)5(11)6(12)4(10)2-9;/h1,3-6,9-12H,2,7H2;1H/t3-,4+,5+,6+;/m0./s1
InChi Key
CBOJBBMQJBVCMW-BTVCFUMJSA-N
Shipping & Storage Information
Storage
4°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 g

    $54

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    250 g

    $106

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    500 g

    $172

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    Product Description

    D-Glucosamine is an amino monosaccharide and a precursor in the biosynthesis of UDP-N-acetyl-D-glucosamine (UDP-GlcNAc; Item No. 20353) via the hexosamine pathway.1,2 It increases mineralization of MC3T3-E1 mouse osteoblastic cells when used at concentrations of 0.1 and 1 mM.3 D-Glucosamine (20 mg/kg per day) inhibits bone erosion and loss of glycosaminoglycans and proteoglycans in joints in a mouse model of collagenase-induced osteoarthritis.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Anderson, J.W., Nicolosi, R.J., and Borzelleca, J.F. Glucosamine effects in humans: A review of effects on glucose metabolism, side effects, safety considerations and efficacy. Food Chem. Toxicol. 43(2), 187-201 (2005).

    2. Ivanovska, N., and Dimitrova, P. Bone resorption and remodeling in murine collagenase-induced osteoarthritis after administration of glucosamine. Arthirits Res. Ther. 13(2), R44 (2011).

    3. Igarashi, M., Sakamoto, K., and Nagaoka, I. Effect of glucosamine, a therapeutic agent for osteoarthritis, on osteoblastic cell differentiation. Int. J. Mol. Med. 28(3), 373-379 (2011).