An inactive control peptide for amyloid-β (1-40)
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Amyloid-β (40-1) Peptide (human) (trifluoroacetate salt)

Item No. 27112

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-valyl-L-valylglycylglycyl-L-valyl-L-methionyl-L-leucylglycyl-L-isoleucyl-L-isoleucyl-L-alanylglycyl-L-lysyl-L-asparaginyl-L-serylglycyl-L-valyl-L-α-aspartyl-L-α-glutamyl-L-alanyl-L-phenylalanyl-L-phenylalanyl-L-valyl-L-leucyl-L-lysyl-L-glutaminyl-L-histidyl-L-histidyl-L-valyl-L-α-glutamyl-L-tyrosylglycyl-L-seryl-L-α-aspartyl-L-histidyl-L-arginyl-L-phenylalanyl-L-α-glutamyl-L-alanyl-L-aspartic acid, trifluoroacetate salt
Synonyms
  • Aβ (40-1)
Molecular Formula
C194H295N53O58S • XCF3COOH
Formula Weight
4329.9
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Formic Acid: 1 mg/ml
SMILES
OC(C(F)(F)F)=O.[H]N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(NCC(NCC(N[C@@H](C(C)C)C(N[C@H](C(N[C@@H](CC(C)C)C(NCC(N[C@]([C@H](CC)C)([H])C(N[C@]([C@H](CC)C)([H])C(N[C@H](C(NCC(N[C@@H](CCCCN)C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(NCC(N[C@@H](C(C)C)C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@H](C(NCC(N[C@@H](CO)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@H](C(O)=O)CC(O)=O)=O)C)=O)=O)CC1=CC=CC=C1)=O)=O)CC2=CN=CN2)=O)CC(O)=O)=O)=O)=O)CC3=CC=C(O)C=C3)=O)=O)=O)CC4=CN=CN4)=O)CC5=CN=CN5)=O)=O)=O)=O)=O)CC6=CC=CC=C6)=O)CC7=CC=CC=C7)=O)C)=O)=O)CC(O)=O)=O)=O)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)CCSC)=O)=O)=O)=O)=O
InChi Code
InChI=1S/C194H295N53O58S.C2HF3O2/c1-25-102(19)158(243-145(258)88-209-163(274)123(67-94(3)4)228-173(284)122(62-66-306-24)226-187(298)154(98(11)12)241-143(256)84-206-140(253)83-211-186(297)153(97(9)10)246-185(296)152(199)96(7)8)192(303)247-159(103(20)26-2)191(302)217-104(21)160(271)207-85-141(254)218-115(47-36-38-63-195)168(279)235-132(76-139(198)252)179(290)240-136(89-248)165(276)210-87-144(257)242-155(99(13)14)188(299)238-134(78-150(267)268)180(291)224-120(56-60-147(261)262)167(278)215-105(22)161(272)227-126(69-107-41-30-27-31-42-107)176(287)231-128(71-109-45-34-29-35-46-109)182(293)244-157(101(17)18)190(301)237-124(68-95(5)6)174(285)220-116(48-37-39-64-196)169(280)222-118(54-58-138(197)251)171(282)232-130(74-112-81-203-92-213-112)178(289)234-131(75-113-82-204-93-214-113)183(294)245-156(100(15)16)189(300)225-121(57-61-148(263)264)172(283)229-125(72-110-50-52-114(250)53-51-110)164(275)208-86-142(255)219-137(90-249)184(295)236-133(77-149(265)266)181(292)233-129(73-111-80-202-91-212-111)177(288)221-117(49-40-65-205-194(200)201)170(281)230-127(70-108-43-32-28-33-44-108)175(286)223-119(55-59-146(259)260)166(277)216-106(23)162(273)239-135(193(304)305)79-151(269)270;3-2(4,5)1(6)7/h27-35,41-46,50-53,80-82,91-106,115-137,152-159,248-250H,25-26,36-40,47-49,54-79,83-90,195-196,199H2,1-24H3,(H2,197,251)(H2,198,252)(H,202,212)(H,203,213)(H,204,214)(H,206,253)(H,207,271)(H,208,275)(H,209,274)(H,210,276)(H,211,297)(H,215,278)(H,216,277)(H,217,302)(H,218,254)(H,219,255)(H,220,285)(H,221,288)(H,222,280)(H,223,286)(H,224,291)(H,225,300)(H,226,298)(H,227,272)(H,228,284)(H,229,283)(H,230,281)(H,231,287)(H,232,282)(H,233,292)(H,234,289)(H,235,279)(H,236,295)(H,237,301)(H,238,299)(H,239,273)(H,240,290)(H,241,256)(H,242,257)(H,243,258)(H,244,293)(H,245,294)(H,246,296)(H,247,303)(H,259,260)(H,261,262)(H,263,264)(H,265,266)(H,267,268)(H,269,270)(H,304,305)(H4,200,201,205);(H,6,7)/t102-,103-,104-,105-,106-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,1
InChi Key
CBKUHMYOPHKUPZ-XGMOOXFWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 µg

    $202

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    Product Description

    Amyloid-β (40-1) peptide (Aβ (40-1)) is a peptide that contains the reverse sequence of Aβ (1-40) peptide (Item No. 21617).1 Aβ (40-1) does not induce neurotoxicity of rat cortical neurons when administered via microinjection into the cerebral cortex at a dose of 3 nmol. It has been used as an inactive control for Aβ (1-40) peptide.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kowall, N.W., Beal, M.F., Busciglio, J., et al. An in vivo model for the neurodegenerative effects of β amyloid and protection by substance P. Proc. Natl. Acad. Sci. USA 88(16), 7247-7251 (1991).

    2. Terranova, J.-P., Kan, J.-P., Storme, J.-J., et al. Administration of amyloid β-peptides in the rat medial septum causes memory deficits: Reversal by SR 57746A, a non-peptide neurotrophic compound. Neurosci. Lett. 213(2), 79-82 (1996).