A flavonoid glucoside
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Complanatuside

Item No. 27295

Technical Information
Formal Name
3-(β-D-glucopyranosyloxy)-2-[4-(β-D-glucopyranosyloxy)phenyl]-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one
CAS Number
116183-66-5
Molecular Formula
C28H32O16
Formula Weight
Purity
≥95%
A crystalline solid
DMF: 10 mg/mlDMSO: 10 mg/mlPBS (pH 7.2): 0.3 mg/ml
λmax
267, 340 nm
SMILES
COC1=CC(O)=C(C(C(O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)=C(C3=CC=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=C3)O5)=O)C5=C1
InChi Code
InChI=1S/C28H32O16/c1-39-12-6-13(31)17-14(7-12)41-25(26(20(17)34)44-28-24(38)22(36)19(33)16(9-30)43-28)10-2-4-11(5-3-10)40-27-23(37)21(35)18(32)15(8-29)42-27/h2-7,15-16,18-19,21-24,27-33,35-38H,8-9H2,1H3/t15-,16-,18-,19-,21+,22+,23-,24-,27-,28+/m1/s1
InChi Key
KKPKUPKKMALLKG-QDYVESOYSA-N
Origin
Plant/Semen Astragali Complanati
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Complanatuside is a flavonoid glucoside originally isolated from A. complanatus.1 It inhibits nitric oxide (NO) production in LPS-stimulated RAW 264.7 cells (IC50 = 21.2 μM).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chen, M.H., and Liu, F.S. Studies on chemical constituents of Astragalus complanatus R. Brown. II. Yao Xue Xue Bao 23(3), 218-220 (1988).

    2. Wang, Z.B., Zhai, Y.D., Ma, Z.P., et alTriterpenoids and flavonoids from the leaves of Astragalus membranaceus and their inhibitory effects on nitric oxide production. Chem. Biodivers. 12(10), 1575-1584 (2015).