A deoxyribonucleoside
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2′-Deoxyadenosine (hydrate)

Item No. 27315

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2'-deoxy-adenosine, monohydrate
CAS Number
16373-93-6
Molecular Formula
C10H13N5O3 • H2O
Formula Weight
269.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 33 mg/mlEthanol: 10 mg/mlPBS (pH 7.2): 1 mg/ml
λmax
260 nm
SMILES
O[C@H]1C[C@H](N2C=NC3=C(N)N=CN=C32)O[C@@H]1CO.O
InChi Code
InChI=1S/C10H13N5O3.H2O/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7;/h3-7,16-17H,1-2H2,(H2,11,12,13);1H2/t5-,6+,7+;/m0./s1
InChi Key
WZJWHIMNXWKNTO-VWZUFWLJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 g

    $49

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    10 g

    $87

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    25 g

    $194

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    Product Description

    2'-Deoxyadenosine is a deoxyribonucleoside and an intermediate in the purine nucleotide degradation pathway.1 It is transported into cells via facilitated diffusion or formed within cells by degradation of S-adenosylhomocysteine or AMP and is removed from cells by purine metabolism or is converted into adenine nucleotides. 2'-Deoxyadenosine has been used in the characterization of DNA conformations and the synthesis of nucleoside analogs as antiviral agents.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fox, I.H., and Kelley, W.N. The role of adenosine and 2'-deoxyadenosine in mammalian cells. Annu. Rev. Biochem. 47, 655-686 (1978).

    2. Katahira, M., Nishimura, Y., Tsuboi, M., et al. Local and overall conformations of DNA double helices with the A - T base pairs. Biochim. Biophys. Acta 867(4), 256-267 (1986).

    3. Ikejiri, M., Oshima, T., Fukushima, A., et al. Synthesis and evaluation of 5'-modified 2'-deoxyadenosine analogues as anti-hepatitis C virus agents. Bioorg. Med. Chem. Lett. 18(16), 4638-4641 (2008).