A benzimidazole anthelmintic
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Oxibendazole

Item No. 27365

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(6-propoxy-1H-benzimidazol-2-yl)-carbamic acid, methyl ester
CAS Number
20559-55-1
Molecular Formula
C12H15N3O3
Formula Weight
249.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 3 mg/mlEthanol: Partially solublePBS (pH 7.2): Partially soluble
λmax
247, 296 nm
SMILES
CCCOC1=CC=C2C(N=C(NC(OC)=O)N2)=C1
InChi Code
InChI=1S/C12H15N3O3/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
InChi Key
RAOCRURYZCVHMG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    25 mg

    $68

    Add

    50 mg

    $105

    Add

    100 mg

    $156

    Add

    250 mg

    $322

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    Oxibendazole is a benzimidazole anthelmintic.1 It inhibits binding of [3H]mebendazole to H. contortus L3 larval tubulin and inhibits mammalian tubulin polymerization (IC50s = 0.3 and 2.2 µM, respectively).1 When used in combination with the anthelmintic niclosamide (Item No. 10649), oxibendazole (15 mg/kg) reduces fecal worm egg counts in dogs and cats by greater than 90% for the nematodes T. canis, T. vulpis, A. caninum, and T. leonine.2 It also reduces fecal egg counts of strongyles in horses when administered at a dose of 10 mg/kg per day.3 Formulations containing oxibendazole have been used in the prevention and treatment of parasitic worm infections in dogs and the treatment of parasitic worm infections in horses.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lacey, E. Mode of action of benzimidazoles. Parasitol. Today 6(4), 112-115 (1990).

    2. Overgaauw, P.A.M., and Boersema, J.H. Anthelmintic efficacy of oxibendazole against some important nematodes in dogs and cats. Vet. Q. 20(2), 69-72 (1998).

    3. Smith, M.A., Nolan, T.J., Rieger, R., et al. Efficacy of major anthelmintics for reduction of fecal shedding of strongyle-type eggs in horses in the Mid-Atlantic region of the United States. Vet. Parasitol. 214(1-2), 139-143 (2015).