An N-terminal peptide fragment of ACTH
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Product Categories

Product Type

Biochemicals
Peptides
Neuropeptides
Peptide Hormones

Research Area

Neuroscience

N-Acetyl ACTH (1-17) (human) (trifluoroacetate salt)

Item No. 27404

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-acetyl-α1-17-corticotropin, trifluoroacetate salt
Synonyms
  • Ac-SYSMEHFRWGKPVGKKR
  • N-Acetyl Adrenocorticotropic Hormone (1-17)
Molecular Formula
C97H147N29O24S • XCF3COOH
Formula Weight
2135.5
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: 1 mg/ml
SMILES
O=C(O)C(F)(F)F.O=C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(N[C@@H](CCCCN)C(N1CCC[C@H]1C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC2=CNC3=C2C=CC=C3)=O)=O)CC4=CC=CC=C4)=O)CC5=CN=CN5)=O)=O)CCSC)=O)=O)CC6=CC=C(O)C=C6)=O)C
InChi Code
InChI=1S/C97H147N29O24S.C2HF3O2/c1-54(2)80(93(147)110-50-77(131)113-63(23-10-13-36-98)82(136)115-64(24-11-14-37-99)83(137)119-69(95(149)150)27-17-40-107-97(103)104)125-92(146)76-28-18-41-126(76)94(148)68(25-12-15-38-100)114-78(132)49-109-81(135)72(45-58-47-108-62-22-9-8-21-61(58)62)122-84(138)65(26-16-39-106-96(101)102)116-87(141)70(43-56-19-6-5-7-20-56)120-89(143)73(46-59-48-105-53-111-59)123-85(139)66(33-34-79(133)134)117-86(140)67(35-42-151-4)118-91(145)75(52-128)124-88(142)71(44-57-29-31-60(130)32-30-57)121-90(144)74(51-127)112-55(3)129;3-2(4,5)1(6)7/h5-9,19-22,29-32,47-48,53-54,63-76,80,108,127-128,130H,10-18,23-28,33-46,49-52,98-100H2,1-4H3,(H,105,111)(H,109,135)(H,110,147)(H,112,129)(H,113,131)(H,114,132)(H,115,136)(H,116,141)(H,117,140)(H,118,145)(H,119,137)(H,120,143)(H,121,144)(H,122,138)(H,123,139)(H,124,142)(H,125,146)(H,133,134)(H,149,150)(H4,101,102,106)(H4,103,104,107);(H,6,7)/t63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,80-;/m0./s1
InChi Key
BUWHNTMPKOEGAD-XDADCBOZSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $112

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    Product Description

    N-Acetyl ACTH (1-17) is an N-terminal peptide fragment of adrenocorticotropic hormone (ACTH), a peptide hormone found in the brain that is involved in the biological stress response.1,2 It has been found in pituitary extracts from Cpefat/fat mice that lack the carboxypeptidase E active form, which is required for processing prohormones.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fenger, M. α-Melanocyte-stimulating-hormone precursors in the pig pituitary. Biochem. J. 235(3), 715-722 (1986).

    2. Strand, F.L., Lee, S.J., Zuccarelli, L.A., et al. Non-corticotropic ACTH peptides modulate nerve development and regeneration. Rev. Neurosci. 4(4), 321-363 (1993).

    3. Che, F.-Y., and Fricker, L.D. Quantitative peptidomics of mouse pituitary: Comparison of different stable isotopic tags. J. Mass. Spectrom. 40(2), 238-249 (2005).