An affinity probe for Aβ40 binding partners
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Biotin-Amyloid-β (1-40) Peptide (trifluoroacetate salt)

Item No. 27411

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-α-aspartyl-L-serylglycyl-L-tyrosyl-L-α-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-α-glutamyl-L-α-aspartyl-L-valylglycyl-L-seryl-L-asparaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-L-methionyl-L-valylglycylglycyl-L-valyl-L-valine, trifluoroacetate salt
Synonyms
  • Biotin-Aβ (1-40)
  • Biotin-Aβ40
Molecular Formula
C204H309N55O60S2 • XCF3COOH
Formula Weight
4556.1
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Formic Acid: 1 mg/ml
SMILES
O=C(N([H])[C@H](C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(N[C@@H](CO)C(NCC(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@@H](C(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(NCC(N[C@H](C(N[C@]([C@H](CC)C)([H])C(N[C@]([C@H](CC)C)([H])C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](C(C)C)C(NCC(NCC(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)=O)=O)CCSC)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)CC(O)=O)=O)=O)C)=O)CC1=CC=CC=C1)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)CC3=CN=CN3)=O)CC4=CN=CN4)=O)=O)=O)CC5=CC=C(O)C=C5)=O)=O)=O)CC(O)=O)=O)CC6=CN=CN6)=O)=O)CC7=CC=CC=C7)=O)=O)C)=O)CC(O)=O)CCCC[C@@H]8SC[C@@](N9)([H])[C@]8([H])NC9=O.O=C(O)C(F)(F)F
InChi Code
InChI=1S/C204H309N55O60S2.C2HF3O2/c1-25-107(19)166(197(312)220-91-151(269)228-128(71-99(3)4)183(298)238-127(66-70-320-24)180(295)252-160(101(7)8)195(310)218-87-148(266)215-88-153(271)251-162(103(11)12)200(315)256-165(106(17)18)202(317)318)258-201(316)167(108(20)26-2)257-171(286)109(21)224-149(267)89-216-172(287)120(49-38-40-67-205)233-190(305)137(80-146(208)264)244-194(309)142(94-261)230-152(270)92-219-196(311)161(102(9)10)253-193(308)140(83-159(282)283)245-178(293)125(60-64-155(274)275)232-169(284)110(22)225-181(296)131(73-112-43-30-27-31-44-112)241-186(301)133(75-114-47-34-29-35-48-114)247-198(313)164(105(15)16)255-192(307)129(72-100(5)6)239-174(289)121(50-39-41-68-206)234-176(291)123(58-62-145(207)263)236-187(302)134(77-116-84-211-96-221-116)243-189(304)136(79-118-86-213-98-223-118)248-199(314)163(104(13)14)254-179(294)126(61-65-156(276)277)237-184(299)130(76-115-54-56-119(262)57-55-115)229-150(268)90-217-173(288)141(93-260)249-191(306)139(82-158(280)281)246-188(303)135(78-117-85-212-97-222-117)242-175(290)122(51-42-69-214-203(209)210)235-185(300)132(74-113-45-32-28-33-46-113)240-177(292)124(59-63-154(272)273)231-170(285)111(23)226-182(297)138(81-157(278)279)227-147(265)53-37-36-52-144-168-143(95-321-144)250-204(319)259-168;3-2(4,5)1(6)7/h27-35,43-48,54-57,84-86,96-111,120-144,160-168,260-262H,25-26,36-42,49-53,58-83,87-95,205-206H2,1-24H3,(H2,207,263)(H2,208,264)(H,211,221)(H,212,222)(H,213,223)(H,215,266)(H,216,287)(H,217,288)(H,218,310)(H,219,311)(H,220,312)(H,224,267)(H,225,296)(H,226,297)(H,227,265)(H,228,269)(H,229,268)(H,230,270)(H,231,285)(H,232,284)(H,233,305)(H,234,291)(H,235,300)(H,236,302)(H,237,299)(H,238,298)(H,239,289)(H,240,292)(H,241,301)(H,242,290)(H,243,304)(H,244,309)(H,245,293)(H,246,303)(H,247,313)(H,248,314)(H,249,306)(H,251,271)(H,252,295)(H,253,308)(H,254,294)(H,255,307)(H,256,315)(H,257,286)(H,258,316)(H,272,273)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,317,318)(H4,209,210,214)(H2,250,259,319);(H,6,7)/t107-,108-,109-,110-
InChi Key
RVQMNOYSPIGZKM-ADLJJDEXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $448

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    Product Description

    Biotin-amyloid-β (1-40) (biotin-Aβ40) is an affinity probe that allows amyloid-β (1-40) (Aβ40) to be detected or immobilized through interaction with the biotin ligand. It has been used to characterize Aβ40 distribution amongst the lipoprotein fractions and identify Aβ40 interaction partners in human plasma.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Koudinov, A., Matsubara, E., Frangione, B., et al. The soluble form of Alzheimer’s amyloid beta protein is complexed to high density lipoprotein 3 and very high density lipoprotein in normal human plasma. Biochem. Biophys. Res. Commun. 205(2), 1164-1171 (1994).