A peptide fragment of histone H2A
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Histone H2A (1-20) (human, mouse, rat, bovine) (trifluoroacetate salt)

Item No. 27440

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-serylglycyl-L-arginylglycyl-L-lysyl-L-glutaminylglycylglycyl-L-lysyl-L-alanyl-L-arginyl-L-alanyl-L-lysyl-L-alanyl-L-lysyl-L-threonyl-L-arginyl-L-seryl-L-seryl-L-arginine, trifluoroacetate salt
Synonyms
  • H-Ser-Gly-Arg-Gly-Lys-Gln-Gly-Gly-Lys-Ala-Arg-Ala-Lys-Ala-Lys-Thr-Arg-Ser-Ser-Arg-OH
  • SGRGKQGGKARAKAKTRSSR
Molecular Formula
C83H155N37O26 • XCF3COOH
Formula Weight
2087.4
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: 1 mg/ml
SMILES
[H]N[C@@H](CO)C(NCC(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(NCC(NCC(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@]([C@@H](C)O)([H])C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)C)=O)=O)C)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C83H155N37O26.C2HF3O2/c1-42(106-70(136)48(17-5-9-27-84)110-60(127)36-102-59(126)35-104-69(135)54(25-26-58(89)125)115-73(139)49(18-6-10-28-85)111-62(129)38-105-68(134)47(21-13-31-98-80(90)91)109-61(128)37-103-67(133)46(88)39-121)66(132)114-52(22-14-32-99-81(92)93)72(138)108-43(2)64(130)112-50(19-7-11-29-86)71(137)107-44(3)65(131)113-51(20-8-12-30-87)75(141)120-63(45(4)124)78(144)116-53(23-15-33-100-82(94)95)74(140)118-57(41-123)77(143)119-56(40-122)76(142)117-55(79(145)146)24-16-34-101-83(96)97;3-2(4,5)1(6)7/h42-57,63,121-124H,5-41,84-88H2,1-4H3,(H2,89,125)(H,102,126)(H,103,133)(H,104,135)(H,105,134)(H,106,136)(H,107,137)(H,108,138)(H,109,128)(H,110,127)(H,111,129)(H,112,130)(H,113,131)(H,114,132)(H,115,139)(H,116,144)(H,117,142)(H,118,140)(H,119,143)(H,120,141)(H,145,146)(H4,90,91,98)(H4,92,93,99)(H4,94,95,100)(H4,96,97,101);(H,6,7)/t42-,43-,44-,45+,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,63-;/m0./s1
InChi Key
LFDBPDADDOUPGV-KPIGGKIJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $112

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    Product Description

    Histone H2A (1-20) is an N-terminal peptide fragment of histone H2A that corresponds to amino acid residues 2-21 of the human histone H2A sequence. Methylation of the arginine at position 3 of histone H2A by protein arginine methyltransferase 1 (PRMT1), PRMT5, or PRMT6 is associated with both transcriptional activation and repression.1 It is associated with DNA damage repair when methylated by PRMT7. The arginine residue at position 3 of histone H2A is also subject to citrullination by protein arginine deiminase 4 (PAD4).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fuhrmann, J., and Thompson, P.R. Protein arginine methylation and citrullination in epigenetic regulation. ACS Chem. Biol. 11(3), 654-668 (2016).