A vital fluorescent dye
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Indocyanine Green

Item No. 27462

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1,1-dimethyl-3-(4-sulfobutyl)-1H-benz[e]indolium, inner salt, monosodium salt
CAS Number
3599-32-4
Synonyms
  • Cardio Green
  • Ujoviridin
Molecular Formula
C43H47N2O6S2 • Na
Formula Weight
775.0
Purity
≥95%
Emission
≥800 nm
Excitation
750-800
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlEthanol: 1 mg/mlPBS (pH 7.2): 0.5 mg/ml
λmax
218, 396, 789 nm
SMILES
CC1(C)C2=C(C=CC3=CC=CC=C32)N(CCCCS([O-])(=O)=O)/C1=C\C=C\C=C\C=C\C4=[N+](CCCCS([O-])(=O)=O)C(C=CC5=CC=CC=C56)=C6C4(C)C.[Na+]
InChi Code
InChI=1S/C43H48N2O6S2.Na/c1-42(2)38(44(28-14-16-30-52(46,47)48)36-26-24-32-18-10-12-20-34(32)40(36)42)22-8-6-5-7-9-23-39-43(3,4)41-35-21-13-11-19-33(35)25-27-37(41)45(39)29-15-17-31-53(49,50)51;/h5-13,18-27H,14-17,28-31H2,1-4H3,(H-,46,47,48,49,50,51);/q;+1/p-1
InChi Key
MOFVSTNWEDAEEK-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $54

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    50 mg

    $85

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    100 mg

    $128

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    250 mg

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    Product Description

    Indocyanine green is a vital fluorescent dye that binds to plasma proteins and lipoproteins.1,2 It displays excitation maxima ranging from 750 to 800 nm and an emission maximum of greater than or equal to 800 nm, which shifts from 810-820 nm in aqueous solution to 820-834 nm following intravenous injection.1,3 Formulations containing indocyanine green have been commonly used in clinical and surgical applications, including retinal angiography, intraocular surgery, and cardiac output and liver condition monitoring.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Alander, J.T., Kaartinen, I., Laakso, A., et al. A review of indocyanine green fluorescent imaging in surgery. Int. J. Biomed. Imaging 940585, (2012).

    2. Morales, M.C., Freire, V., Asumendi, A., et al. Comparative effects of six intraocular vital dyes on retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 51(11), 6018-6029 (2010).

    3. Desmettre, T., Devoisselle, J.M., and Mordon, S. Fluorescence properties and metabolic features of indocyanine green (ICG) as related to angiography. Surv. Ophthalmol. 45(1), 15-27 (2000).