A peptide fragment of histone H3
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Histone H3 (1-35) (human, mouse, rat, bovine) (trifluoroacetate salt)

Item No. 27524

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-alanyl-L-arginyl-L-threonyl-L-lysyl-L-glutaminyl-L-threonyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-threonylglycylglycyl-L-lysyl-L-alanyl-L-prolyl-L-arginyl-L-lysyl-L-glutaminyl-L-leucyl-L-alanyl-L-threonyl-L-lysyl-L-alanyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-prolyl-L-alanyl-L-threonylglycylglycyl-L-valine, trifluoroacetate salt
Synonyms
  • ARTKQTARKSTGGKAPRKQLATKAARKSAPATGGV
Molecular Formula
C149H269N55O45 • XCF3COOH
Formula Weight
3551.1
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: 1 mg/ml
SMILES
O=C(O)C(F)(F)F.[H]N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@]([C@@H](C)O)([H])C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@]([C@@H](C)O)([H])C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@]([C@@H](C)O)([H])C(NCC(NCC(N[C@@H](CCCCN)C(N[C@H](C(N1CCC[C@H]1C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@]([C@@H](C)O)([H])C(N[C@@H](CCCCN)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@H](C(N2CCC[C@H]2C(N[C@H](C(N[C@]([C@@H](C)O)([H])C(NCC(NCC(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)=O)C)=O)=O)C)=O)=O)=O)=O)C)=O)C)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)C
InChi Code
InChI=1S/C149H269N55O45.C2HF3O2/c1-71(2)64-98(133(236)177-77(9)119(222)199-113(84(16)210)141(244)192-87(37-19-25-53-151)122(225)176-74(6)116(219)175-75(7)117(220)184-92(42-30-58-167-146(159)160)125(228)187-89(39-21-27-55-153)128(231)195-99(69-205)134(237)181-80(12)144(247)203-62-34-46-101(203)136(239)178-78(10)120(223)198-110(81(13)207)138(241)173-66-106(215)172-68-108(217)197-109(72(3)4)145(248)249)194-130(233)96(48-50-103(157)212)189-123(226)88(38-20-26-54-152)186-127(230)94(44-32-60-169-148(163)164)191-137(240)102-47-35-63-204(102)143(246)79(11)180-121(224)86(36-18-24-52-150)182-107(216)67-171-105(214)65-174-139(242)111(82(14)208)200-135(238)100(70-206)196-129(232)90(40-22-28-56-154)188-126(229)93(43-31-59-168-147(161)162)185-118(221)76(8)179-140(243)112(83(15)209)201-132(235)97(49-51-104(158)213)190-124(227)91(41-23-29-57-155)193-142(245)114(85(17)211)202-131(234)95(183-115(218)73(5)156)45-33-61-170-149(165)166;3-2(4,5)1(6)7/h71-102,109-114,205-211H,18-70,150-156H2,1-17H3,(H2,157,212)(H2,158,213)(H,171,214)(H,172,215)(H,173,241)(H,174,242)(H,175,219)(H,176,225)(H,177,236)(H,178,239)(H,179,243)(H,180,224)(H,181,237)(H,182,216)(H,183,218)(H,184,220)(H,185,221)(H,186,230)(H,187,228)(H,188,229)(H,189,226)(H,190,227)(H,191,240)(H,192,244)(H,193,245)(H,194,233)(H,195,231)(H,196,232)(H,197,217)(H,198,223)(H,199,222)(H,200,238)(H,201,235)(H,202,234)(H,248,249)(H4,159,160,167)(H4,161,162,168)(H4,163,164,169)(H4,165,166,170);(H,6,7)/t73-,74-,75-,76-,77-,78-,79-,80-,81+,82+,83+,84+,85+,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,109-,110-,111-,112-,113-,114-;/m0./s1
InChi Key
KEDLXRCGKAMCGQ-XQSSRABOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    250 µg

    $336

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    Product Description

    Histone H3 (1-35) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-36 of the human histone H3.1 and 3.2 sequences. Histone H3 (1-35) contains lysine residues at positions 4, 9, and 27 that are subject to methylation and acetylation and a serine residue at position 10 that is subject to phosphorylation, all of which have a role in the regulation of gene expression.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bhaumik, S.R., Smith, E., and Shilatifard, A. Covalent modifications of histones during development and disease pathogenesis. Nat. Struct. Mol. Biol. 14(11), 1008-1016 (2007).