A flavonoid glycoside
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Epimedin A

Item No. 27582

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-[(6-deoxy-2-O-β-D-glucopyranosyl-α-L-mannopyranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
CAS Number
110623-72-8
Molecular Formula
C39H50O20
Formula Weight
838.8
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mLDMSO: 10 mg/mLEthanol: 2 mg/mLPBS (pH 7.2): 3 mg/mL
λmax
273, 317 nm
SMILES
C/C(C)=C/CC1=C2C(C(C(O[C@H]3[C@H](O[C@]4([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H](O)[C@@H](O)[C@H](C)O3)=C(C5=CC=C(OC)C=C5)O2)=O)=C(O)C=C1O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O6
InChi Code
InChI=1S/C39H50O20/c1-14(2)5-10-18-20(54-37-31(50)28(47)25(44)21(12-40)55-37)11-19(42)23-27(46)35(33(57-34(18)23)16-6-8-17(52-4)9-7-16)58-39-36(30(49)24(43)15(3)53-39)59-38-32(51)29(48)26(45)22(13-41)56-38/h5-9,11,15,21-22,24-26,28-32,36-45,47-51H,10,12-13H2,1-4H3/t15-,21+,22+,24-,25+,26+,28-,29-,30+,31+,32+,36+,37+,38-,39-/m0/s1
InChi Key
SVXJDTNFJXKATR-BTXBWYRTSA-N
Origin
Plant/Epimedium sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $63

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    10 mg

    $119

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    25 mg

    $283

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    50 mg

    $502

    Add
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    Product Description

    Epimedin A is a flavonoid glycoside that has been found in Epimedium.1 It inhibits ear edema induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mice (ED50 = 252 nmol/ear). Epimedin A also prevents osteoporosis induced by prednisolone (Item No. 20866) in zebrafish.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yasukawa, K., Ko, S.-K., and Whang, W.-K. Inhibitory effects of the aerial parts of Epimedium koreanum on TPA-induced inflammation and tumour promotion in two-stage carcinogenesis in mouse skin. J. Pharm. Nutr. Sci. 6(2), 38-42 (2016).

    2. Zhan, Y., Wei, Y.J., Sun, E., et al. Two-dimensional zebrafish model combined with hyphenated chromatographic techniques for evaluation anti-osteoporosis activity of epimendin A and its metabolite baohuoside I. Yao Xue Xue Bao 49(6), 932-937 (2014).