A solvatochromic fluorescent probe
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Prodan

Item No. 27663

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[6-(dimethylamino)-2-naphthalenyl]-1-propanone
CAS Number
70504-01-7
Synonyms
  • N,N-Dimethyl-6-propionyl-2-naphthylamine
Molecular Formula
C15H17NO
Formula Weight
227.3
Purity
≥98%
Emission
416 nm in toluene; increases as solvent polarity increases
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMF:PBS (pH 7.2) (1:2): 0.3 mg/mlDMSO: 5 mg/mlEthanol: 1 mg/ml
λmax
231, 250, 259, 283, 359 nm
SMILES
CCC(C1=CC2=C(C=C1)C=C(N(C)C)C=C2)=O
InChi Code
InChI=1S/C15H17NO/c1-4-15(17)13-6-5-12-10-14(16(2)3)8-7-11(12)9-13/h5-10H,4H2,1-3H3
InChi Key
MPPQGYCZBNURDG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    100 mg

    $134

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    250 mg

    $251

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    500 mg

    $399

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    1 g

    $598

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    Product Description

    Prodan is a solvatochromic fluorescent probe.1 It exhibits absorbance/emission maxima of 347/416 nm, respectively, in toluene, with both parameters increasing as solvent polarity increases. The emission maximum is also influenced by the phase state of membranes, such as in multilamellar vesicles containing 1,2-dipalmitoyl-sn-glycero-3-PC (DPPC; Item No. 10009473) wherein the emission maximum of prodan shifts from approximately 440 nm in the gel phase to approximately 490 nm in the liquid crystalline phase.2 Prodan has been used to probe the microenvironmental conditions of biological and synthetic membranes.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kucherak, O.A., Didier, P., Mély, Y., et al. Fluorene analogues of prodan with superior fluorescence brightness and solvatochromism. J. Phys. Chem. Lett. 1(3), 616-620 (2010).

    2. Parasassi, T., Krasnowska, E.K., Bagatolli, L., et al. Laurdan and prodan as polarity-sensitive fluorescent membrane probes. J. Fluoresc. 8(4), 365-373 (1998).

    3. Mennucci, B., Caricato, M., Ingrosso, F., et al. How the environment controls absorption and fluorescence spectra of PRODAN: A quantum-mechanical study in homogeneous and heterogeneous media. J. Phys. Chem. B 112(2), 414-423 (2008).